The cytogenetic changes in the thyroid cells of 199 Fischer rats are reported here. Fifty -eight rats were maintained on a normal iodine diet and 141 rats were maintained on an iodinedeficient diet for 7-25 months. Rats were sacrificed in groups of two to ten at two-week to one-month intervals; their thyroid cells were grown in cell culture and prepared for chromosomal analyses. An average of 4...

THE INTERNATIONAL COUNCIL FOR CONTROL OF IODINE DEFICIENCY DISORDERS (ICCIDD) is a nonprofit, nongovernmental organization dedicated to sustained optimal iodine nutrition and the elimination of iodine deficiency throughout the world. Its activities have been supported by the international aid programs of Australia, Canada, Netherlands, USA, and also by funds from UNICEF, the World Bank and othe...

BACKGROUND Several studies pertaining to current status of Iodine Deficiency Disorder Control Programme in India have revealed goiter prevalence in the range of 1.5-44.5%, mean urinary iodine excretion level ranging from 92.5-160 mcg/L and iodized salt coverage ranging from 37-62.3%. Most of these studies were based on school children. However, very few studies have focused on pregnant women. T...

High dietary salt is a major cause of increased blood pressure, the leading risk for death worldwide. The World Health Organization (WHO) has recommended that salt intake be less than 5 g/day, a goal that only a small proportion of people achieve. Iodine deficiency can cause cognitive and motor impairment and, if severe, hypothyroidism with serious mental and growth retardation. More than 2 bil...

Different strategies have been developed to ensure a better iodine supply for man. The most common one is the iodisation of salt, but since the application is voluntary, it has not been effective enough. There still is a mild to moderate deficiency in the iodine intake of man of about 30 % in Germany [2, 6, 8]. Another strategy to fight iodine deficiency is to supplement animal feed with iodine...

BACKGROUND In developing countries, many children are at high risk of goiter and iron deficiency anemia. Because iron deficiency can have adverse effects on thyroid metabolism, iron deficiency may influence the response to supplemental iodine in areas of endemic goiter. OBJECTIVE The aim of this study was to determine whether goitrous children with iron deficiency anemia would respond to oral...

Iodine deficiency is well known as a cause of several disorders such as endemic goiter and cretinism, along with a wide spectrum of psychoneurologic development disorders including endemic mental deficiency, which are generally correlated with damage to the fetus. Since as much as 40% of the Tanzanian population is at risk for iodine deficiency disorders (IDD) because they live in iodine-defici...

BACKGROUND Iodine deficiency is a global public health problem, and estimates of the extent of the problem were last produced in 2003. OBJECTIVES To provide updated global estimates of the magnitude of iodine deficiency in 2007, to assess progress since 2003, and to provide information on gaps in the data available. METHODS Recently published, nationally representative data on urinary iodin...

OBJECTIVE Iodine deficiency and excess are the most important factors that affect screening and recall rates of congenital hypothyroidism. The purpose of this study was to investigate the urinary iodine status in newborns and their mothers and its effects on neonatal thyroid-stimulating hormone (TSH) levels in a mildly iodine-deficient area. METHODS A total of 116 newborns and their mothers w...

OBJECTIVE To determine the iodine content of iodized salt at the production stage, to assess the perceptions and knowledge of salt producers about the prevention and control of iodine deficiency, and to examine the internal quality control procedures used during iodization in South Africa. METHOD Salt samples were collected for iodine analysis by titration from the 12 producers iodizing salt ...