AIM To document ocular outcome in premature infants with intraventricular haemorrhages (IVH). METHODS 68 preterm infants with IVH were examined. RESULTS Mean gestational age was 28.1 weeks (range 24-35). Mean birth weight was 1045.9 g (630-2240). Mean follow up was 54.6 months (6-150). IVH is graded from 1 to 4 based on the severity of haemorrhages. The incidence of ocular abnormalities was...

In a prospective study at Sultan Qaboos University Hospital, 95 premature infants with birthweights equal or less than 1500 g were screened for intraventricular haemorrhage (IVH) using cranial ultrasound. Nineteen (20 per cent) were found to have developed IVH. Eight out of fourteen variables studied showed a significant difference between infants who did and those who did not develop IVH. Thes...

BACKGROUND To explore the associations between histologic chorioamnionitis with brain injury, maturation and size on magnetic resonance imaging (MRI) of preterm infants at term equivalent age. METHODS Preterm infants (23-36 weeks' gestational age) were recruited into two longitudinal cohort studies. Presence or absence of chorioamnionitis was obtained from placental histology and clinical dat...

In other conditions associated with placental oedema-such as the fetofetal transfusion syndrome, and hydrops fetalis due to rhesus isoimmunisation or congenital syphilis-low levels of the maternally synthesised immunoglobulin IgG have been found in the cord bloods of the infants.7 8 These findings suggest that placental transfer ofIgG is also reduced. We, like Chiang and Wei,7 found that the co...

A 37 year old Vietnamese woman 30 weeks into her first pregnancy presented with sudden severe headache and progression to unconsciousness over 30 minutes. In 1991 she was diagnosed as having migraine and a single generalised convulsion; an EEG and brain CT at that time were normal. There was no family history of note and she was taking no medication. On admission she was obtunded with pronounce...

The brains of 30 infants who died after at least one real time ultrasound scan were examined after fixation. The ultrasound diagnosis of either periventricular haemorrhage or periventricular leucomalacia was compared with the macroscopic and histological appearances. Each hemisphere was considered separately for both periventricular haemorrhage and periventricular leucomalacia. The accuracy of ...

AIMS The study is an integrated assessment of clinical, image and morphological parameters in severe intracerebral haemorrhages (ICH) complicated with intraventricular extension (IVE). MATERIAL AND METHODS The studied group had 93 cases of patients with ICH and IVE who were hospitalized in the Emergency County Hospital of Craiova and died during hospitalization. The parameters evaluated were ...

Intraventricular haemorrhage (IVH) is the most common brain lesion in preterm infants. The prognosis is dire and there is no available therapy to prevent infants from developing either post-haemorrhagic ventricular dilatation (PHVD) or serious neurological disability. Mechanisms leading to brain damage and hydrocephalus following IVH are complex and incompletely understood. Our working hypothes...

A technique has been developed for the injection and stereomicroscopic examination of blood vessels in the preterm newborn brain. Using this technique it can be seen that in the immature brain there is a rich capillary bed in the germinal layer region supplied mainly by Heubner's artery. Capillary channels drain directly into the terminal vein and its main branches. Study of 19 cases with spont...

Continuous measurements of arterial pressures, heart rates, respiratory movements, and respiratory rates were made from birth in 44 infants at risk from intraventricular haemorrhage (IVH). 17 babies died with IVH, in 10 of whom the event was timed objectively. Events in these babies were compared with survivors of similar birthweights, gestational ages, severity of birth asphyxia, and severity ...