Abstract Background Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are syndromes of failure with extremely high mortality few effective treatments. Mesenchymal stem cells (MSCs) may reportedly contribute to tissue repair in ALI ARDS. However, applications MSCs have been restricted due safety considerations limitations terms large-scale production industrial delivery. Alt...

INTRODUCTION: Thyroid ectopia can be found at the site of thyroid origin in the floor of the mouth, or anywhere along its path of embryological descent, thus reflecting the normal migration of thyroid progenitor cells. The most frequent sites of ectopic thyroid tissue are lingual, sublingual, thyroglossal and laryngotracheal, with ectopic intratracheal thyroid (EITT) accounting for a small mino...

Surgeon to the Bristol General Hospital.

A 39-yr-old woman presented with dyspnea and cough. She had undergone total thyroidectomy for multinodular goiter 15 yr earlier, with subsequent T4 replacement therapy. Inspiratory stridor was noted. Serum TSH was 2.95 mIU/ml (normal, 0.3–4.0 mIU/ml). A magnetic resonance image (MRI) of the neck showed a subglottic tumor with severe occlusion of the trachea (Figs. 1 and 2). Direct laryngoscopy ...

BACKGROUND Targeted delivery of gene therapy vectors to the mouse respiratory tract is often performed via intranasal or intratracheal administration; however, there can be a great deal of variability between these methods, which could potentially influence experimental results. Improving the accuracy and precision of lung delivery will not only reduce the number of animals required to detect s...

INTRODUCTION Clearance of alveolar oedema depends on active transport of sodium across the alveolar-epithelial barrier. beta-Adrenergic agonists increase clearance of pulmonary oedema, but it has not been established whether beta-agonist stimulation achieves sufficient oedema clearance to improve survival in animals. The objective of this study was to determine whether the increased pulmonary o...

Background: Acute organophosphate poisoning (AOPP) is related to several clinical complications that may be fatal. The aim of this study was to evaluate the effects of demographic, clinical and laboratory findings on AOPP outcome. Methods: In this retrospective cross-sectional study, medical records of all patients with AOPP admitted to Imam Reza Hospital, Mashhad, Iran, were reviewed from Jan...