Lornoxicam (Lnxc), a novel type of non-steroidal antiinflammatory drug developed by comely, was first listed in Denmark in October 1997 (trade name xefo). Clinically, it is used to treat rheumatoid, rheumatoid arthritis and osteoarthritis. The Lnxc with low drug concentration has a short half-life [1] after oral administration, leading to much side effect and therapy activity tended to be worse...

pseudo-aneurysm of the femoral artery is the most common arterial complication in drug injecting abusers. scholars in vascular surgery have published debating statements regarding techniques of successful surgical management during last two decades. we present the results of simple arterial ligation in a series of 32 patients presenting with infected femoral pseudo-aneurysm. most of the patient...

Gene therapy has the potential to provide therapeutic benefits to hepatocellular carcinoma (HCC) patients and has been the subject of intense pre-clinical and clinical research in recent years. In HCC, delivery of gene therapy has been attempted through multiple routes, using many vectors and genes in both animal models and patients. Unfortunately, a highly effective gene therapy for HCC has no...

Epidural steroid injections (ESIs) as minimally invasive procedures have been widely used for the relief of neck, arm, back, and leg pain potentially due to spinal stenosis, spondylolysis, or disc herniation. In rare instances, ESI therapy may cause clinical complications, some of which can be catastrophic. The surgical procedure itself including needle penetration, the potential use of contras...

Arterial complications from inadvertent arterial puncture in intravenous drug abusers are well recognised. Most reports describe injury to the femoral artery with occasional reports of brachial and radial artery injury. A case of subclavian artery injury is described in this paper, and the pathophysiology and treatment of intraarterial drug injection discussed.

Objectives: Popular animal models of septic shock involve injections endotoxin (bacterial lipopolysaccharide). Other methods that induce sepsis are often time-consuming and require long-term monitoring facilities. Further, individual using different bacterial strains can deepen our understanding pathophysiology. Hence, objective was to develop an acute functional Wistar rat model live Escherich...