NSAIDuse is limited due to the drugs' toxicity to the gastrointestinal mucosa, an action incompletely understood. Lower gut injury induced byNSAIDs is dependent on bile secretion and is reported to increase the growth of a number of bacterial species, including an enterococcal species,Enterococcus faecalis This study examined the relationships between indomethacin (INDO)-induced intestinal inju...

Our body is able to make use of the metabolic sources in the environment by way of the alimentary tract. In order for it to serve as a conduit for the food and other essential substances, it has to undergo specific functions such as food propulsion, secretion of digestive juices, and absorption of simplified nutrients and vitamins, among others. Needless to say, any interruptions in the continu...

et al,' in which the authors demonstrated an altered character in the small bowel's bacterial flora in patients with rheumatoid arthritis. However, the authors did not demonstrate the presence of bacterial overgrowth. The syndrome of bacterial overgrowth is characterised by diarrhoea with malabsorption. The mechanism by which the bacterial overgrowth causes symptoms is not known. These symptoms...

BACKGROUND Gut microbiota plays several beneficial effects on the human host. Its qualitative and/or quantitative unbalance may facilitate the occurrence of small intestinal bacterial overgrowth (SIBO). AIM To review the available data in order to propose a practical approach to SIBO diagnosis in the clinical setting. MATERIALS AND METHODS Full papers from 1990 to present available on the P...

Received: December 12, 2015 Revised: None Accepted: December 14, 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons. org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. *Correspondence: Chan...

Three cases are described of end stage chronic intestinal pseudo-obstruction successfully treated by subtotal enterectomy and home parenteral nutrition (HPN). In all three patients prior use of drugs to stimulate gastrointestinal motility, antibiotics to suppress bacterial overgrowth and surgical bypass of dilated bowel had failed to alleviate the symptoms of chronic intestinal obstruction. Sim...

Background and Aim: The prebiotic potential of lactulose is well known, but its effect to inhibit enteric bacterial dynamics gut permeability has not yet been investigated in experimental studies. present study aims assess the effects on a model bile duct ligation Wistar rats. Methods: rats were assigned into 3 groups, Sham-operated control, ligated (BDL) BDL+ Lac group 28th day ligation. Anima...