Introduction: Seismic damage affecting the non-structural components of buildings (such as infills) can significantly impact expected economic losses over a structure’s service life. Recently, autoclaved aerated concrete (AAC) infills have gained attention in construction industry due to their light weight, energy efficiency, and durability. Methods: This study investigates out-of-plane behavio...

Case fatality rates for severe malaria remain high even in the best clinical settings because antimalarial drugs act against the parasite without alleviating life-threatening inflammation. We assessed the potential for host-directed therapy of severe malaria of a new class of anti-inflammatory drugs, the innate defense regulator (IDR) peptides, based on host defense peptides. The Plasmodium ber...

BACKGROUND In this paper, we analyze the effectiveness of the Integrated Dynamic Representation strategy (IDR) to develop basic math skills. METHOD The study involved 72 students, aged between 6 and 8 years. We compared the development of informal basic skills (numbers, comparison, informal calculation, and informal concepts) and formal (conventionalisms, number facts, formal calculus, and fo...

Measurement of the statistical reproducibility between biological experiment replicates is vital first step of the entire series of bioinformatics analysis for mining meaningful biological discovery from mega-data. To distinguish the real biological relevant signals from artificial signals, irreproducible discovery rate (IDR) employing Copula, which can separate dependence structure and margina...

The inter-story drift ratio (IDR) is a crucial parameter in structural health monitoring to judge the safety, stability, and serviceability of buildings. Real-time, continuous, widely applicable detection on IDRs essential. However, current methods present some challenges conducting such detection, including adverse effects from weather, requirement for large amounts space, fragile instruments....

BACKGROUND The only human cathelicidin, LL-37, and the innate defense regulator peptide IDR-1, which have been proven to have antimicrobial activity, represent essential elements of immunity. Our previous study showed that the peptide LL-37 was protective in vitro to attenuate LTA-induced inflammatory effects. Methicillin-resistant staphylococcus aureus (MRSA) causes a multitude of serious and ...

OBJECTIVE There is currently no pharmacological treatment that provides protection against brain injury in neonates. It is known that activation of an innate immune response is a key, contributing factor in perinatal brain injury; therefore, the neuroprotective therapeutic potential of innate defense regulator peptides (IDRs) was investigated. METHODS The anti-inflammatory effects of 3 IDRs w...

This study deals with performance-based design optimization (PBDO) of steel moment frames employing four different metaheuristics consisting of genetic algorithm (GA), ant colony optimization (ACO), harmony search (HS), and particle swarm optimization (PSO). In order to evaluate the seismic capacity of the structures, nonlinear pushover analysis is conducted (PBDO). This method is an iterative ...

For simplicity, we follow the rules: S denotes a 1-sorted structure, R denotes a non empty 1-sorted structure, X denotes a subset of the carrier of R, T denotes a non empty topological structure, and x denotes a set. Let X, Y be sets. One can verify that every function from X into Y which is bijective is also one-to-one and onto and every function from X into Y which is one-to-one and onto is a...