To investigate the effect and related mechanism of propofol anesthesia on pyroptosis in neonatal rat hippocampus. Neonatal rats were divided into a control group (injected intraperitoneally with saline), 80 mg/kg propofol) propofol+MCC950 10 MCC950) administered for 5 d. The day after end drug administration, hippocampi analyzed by transferase dUTP nick labeling assay interleukin beta-1, interl...