Staphylococcus aureus is one of the bacteria that causes postpartum infection, where this bacterium releases peptidoglycans and lipoteichoic acid (LTA) start inflammation response, which then responded by macrophages releasing pro-inflammation cytokines such as Tumor Necrosis Factor-Alpha (TNF-α) Interleukin 1-Beta (IL-1β). Red Turi leaf extract, known to contain saponins, flavonoids, tannins w...

The aim of the present study was to determine the effect of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) and interleukin-6 (IL-6) on prostaglandin (PG)F2α and PGE2 secretion as well as cyclooxygenase-2 (COX-2) protein expression in chorioamnion collected on days 25, 30 and 40 of pregnancy in pigs. Fetal membrane slices were incubated for 16 h with TNF-α, IL-1β, IL-6 (1 or 10 ng/ml of...

BACKGROUND Insulin resistance (IR) and inflammation are associated with increased risk of complications in chronic kidney disease (CKD) patients. However, the relationship between IR and the important proinflammatory interleukin-1β (IL-1β) is unclear in CKD patients. MATERIAL AND METHODS We conducted a cross-sectional study including 79 non-diabetic patients who received hemodialysis after the ...

Cartilage erosion in degenerative joint diseases leads to lameness in affected horses. It has been reported that andrographolide from Andrographis paniculata inhibited cartilage matrix-degrading enzymes. This study aimed to explore whether this compound protects equine cartilage degradation in the explant culture model and to determine its effect on matrix metalloproteinase-2 (MMP-2) expression...

interleukin-1β (il-1β) has a role in β- cell destruction in autoimmune diabetes by stimulating the expression of inducible nitric oxide synthase (inos) that generates the free radical nitric oxide. we aimed to investigate the effect of achillea millefolium l, as a traditional hypoglycemic agent, on il-1β and inos gene expression of pancreatic tissue in the stz- induced diabetic rats. forty adul...

The effect of Sargassum pallidum (brown seaweed) aqueous extract on the immunity function and antioxidant activities in was studied gastric cancer rats. Treatment with Sargassum pallidum aqueous extract at oral doses 400, 600 or 800 mg/kg body weight was found to provide a dose-dependent protection against N-methyl-N′-nitro-Nnitrosoguanidine (MNNG)-induced immunity damage and oxidative injury b...

As an attempt to prevent transition-period-associated metabolic disorders and/or diseases, the potential benefits of Boswellia sacra (Bs) resin on hematology, immunity, status, udder and uterus health biomarkers, milk production were examined in transitioning goats. From 2 weeks prepartum 7 postpartum, goats (n = 7/treatment) orally received 0 (control, nBS), (BsL), or 4 (BsH) g Bs resin/goat/d...

The literature lacks consensus on the minimum microbial density required for diagnosing urinary tract infections (UTIs). This study categorized densities of urine specimens from symptomatic UTI patients aged ≥ 60 years and correlated them with detected levels immune response biomarkers neutrophil gelatinase-associated lipocalin (NGAL), interleukin-8 (IL-8), interleukin-1-beta (IL-1β). objective...

INTRODUCTION Hepatitis C virus (HCV) infection results in chronic hepatitis in more than 70% of infected patients, while 20-30% of patients recover spontaneously. This strengthens the role of the host genetic factors in either spontaneous or drug-induced viral clearance. The aim of this study was to investigate the relationship between interleukin-1β +3953 gene polymorphism and the response to ...