نتایج جستجو برای: interferon alfa

تعداد نتایج: 81290  

Journal: :Gastroenterology 1997
B Gavier M A Martínez-González J I Riezu-Boj J J Lasarte N Garcia M P Civeira J Prieto

BACKGROUND & AIMS In chronic hepatitis C, interferon alfa induces sustained remission in less than 30% of treated patients. The aim of this study is to analyze viral status early after initiation interferon therapy as a predictor of treatment outcome. METHODS One hundred eighty-one patients with chronic hepatitis C who had been treated with interferon alfa for 12 months (median follow-up, 49 ...

Journal: :Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2007
Peter J Tebben John L D Atkinson Bernd W Scheithauer Dana Erickson

OBJECTIVE To describe a case of granulomatous hypophysitis occurring after treatment with interferon alfa-2b and ribavirin for hepatitis C. METHODS Clinical, radiologic, laboratory, and pathologic assessments of a woman with granulomatous hypophysitis and interferon-induced thyroiditis are presented. RESULTS A 42-year-old woman with hepatitis C was treated with interferon alfa-2b and ribavi...

Journal: :The Journal of antimicrobial chemotherapy 2007
D Aguilar Marucco L Veronese D Gonzalez de Requena S Bonora A Calcagno I Cavecchia A Sinicco F G De Rosa G Cariti G Di Perri

OBJECTIVES To evaluate the early anti-HIV activity of pegylated interferon (PEG-IFN) alfa-2a and ribavirin in HIV/hepatitis C virus (HCV) co-infected patients not receiving antiretroviral therapy. PATIENTS AND METHODS In 19 patients with baseline plasma HIV load (HIV-RNA) >1000 copies/mL treated with PEG-IFN alfa-2a and ribavirin, HIV-RNA and T-cell subsets were measured at baseline and 2, 4 ...

2016
Graham R. Foster Kazuaki Chayama Wan-Long Chuang Hugo Fainboim Martti Farkkila Adrian Gadano Giovanni B. Gaeta Christophe Hézode Yukiko Inada Jeong Heo Hiromitsu Kumada Sheng-Nan Lu Patrick Marcellin Christophe Moreno Stuart K. Roberts Simone I. Strasser Alexander J. Thompson Joji Toyota Seung Woon Paik John M. Vierling Anna L. Zignego David Cohen Fiona McPhee Megan Wind-Rotolo Subasree Srinivasan Matthew Hruska Heather Myler Simon D. Portsmouth

BACKGROUND AND PURPOSE Peginterferon Lambda was being developed as an alternative to alfa interferon for the treatment of chronic hepatitis C virus (HCV) infection. We compared peginterferon Lambda-1a plus ribavirin (Lambda/RBV) and Lambda/RBV plus daclatasvir (DCV; pangenotypic NS5A inhibitor) with peginterferon alfa-2a plus RBV (alfa/RBV) in treatment-naive patients with HCV genotype 2 or 3 i...

2015
Yonghong Zhu

In 1989, scientists at Chiron (acquired by Novartis in 2006), in collaboration with a CDC researcher, first reported the molecular cloning of hepatitis C virus (HCV) genome from serum samples of patients diagnosed with Non-A Non-B viral hepatitis [1]. After the discovery of HCV, tremendous progress has been made toward better understanding the virus itself and its associated chronic hepatitis C...

Journal: :Medical and pediatric oncology 2003
Herwig Lackner Christian Urban Hans Jürgen Dornbusch Wolfgang Schwinger Reinhold Kerbl Petra Sovinz

1. Webber BL, Parham DM, Drake LG, et al. Renal tumors in childhood. Pathol Ann Part 1992;1:191–232. 2. Murphy WM, Beckwith JB, Farrow GM. Tumors of the kidney, bladder and related urinary structures. In: Murphy WM, Beckwith JB, Farrow GM, editors. Atlas of tumor pathology, series 3, fascicle 11. Washington D.C.: Armed Forces Institute of Pathology, 1994. 3. Beckwith JB. Pediatric neoplastic di...

Journal: :iranian journal of medical sciences 0
z. rezaieyazdi department of internal medicine, division of rheumatology, mashhad university of medical sciences, mashhad, iran. g. shoja-e-razavi department of internal medicine, division of rheumatology, mashhad university of medical sciences, mashhad, iran.

background: viral infections such as epstein-barr virus and herpes simplex virus may play a role in the pathogenesis of behçet’s disease (bd). interferons (inf) are natural defense mechanisms against viruses and inhibit their activities by enhancing major histocompatibility complex class i and cytokine expression. this study evaluated the efficacy of inf-α-2b on mucocutaneous lesions of bd.   m...

Journal: :Indian pediatrics 2005
V Manchanda Y K Sarin

1. Beedassy A, Topolsky D, Styler M, Crilley P. Extramedullary blast crisis in a patient with chronic myeloid leukemia in complete cytogenetic and molecular remission on interferon alfa therapy. Leukemia 2000; 24: 733-735. 2. Carlson NL, Erichson G, Lissel L. Simultaneous meningeal and testicular lymphoblastic transformation of Philadelphia positive CML in a three year old. Anticancer Res 1990;...

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