In the era of intensity-modulated radiation therapy, image-guided radiotherapy (IGRT) appears crucial to control dose delivery and to promote dose escalation while allowing healthy tissue sparing. The place of IGRT following radical prostatectomy is poorly described in the literature. This review aims to highlight some key points on the different IGRT techniques applicable to prostatic bed radi...

PURPOSE The aim of this study was to compare dosimetric characteristics, monitor unit, and delivery efficiency of 4 different stereotactic body radiotherapy techniques for the treatment of prostate cancer. METHODS This study included 8 patients with localized prostate cancer. Dosimetric assets of 4 delivery techniques for stereotactic body radiotherapy were evaluated: robotic CyberKnife, nonc...

Internal organ motion during radiation therapy, if not considered appropriately in the planning process, has been shown to reduce target coverage and increase the dose to healthy tissues. Standard planning approaches, which use safety margins to handle intrafractional movement of the tumor, are typically designed based on the maximum amplitude of motion, and are often overly conservative. Compa...

Radiation therapy is a cornerstone in the therapeutic management of craniopharyngioma. The close proximity to neighboring eloquent structures pose a particular challenge to radiation therapy. Modern treatment technologies including fractionated 3-D conformal radiotherapy, intensity modulated radiation therapy, and recently proton therapy are able to precisely cover the target while preserving s...

To evaluate the utility of Dynalog file information for planar dose verification in IMRT QA, a program is developed to convert Dynalog file data to DMLC field files. For this study, five predefined fluencies are planned and delivered using Varian, Eclipse 3D planning system and 6MV photon beam of Varian, Clinac DMX linear accelerator. To measure planar dose distribution, Kodak, EDR2 films are e...

This paper presents the results of a one year survey of treated fields for 3 treatment machines at our New Jersey regional center. One machine predominantly treated IMRT prostate patients using a sliding window technique. The others were not equipped to deliver IMRT. Information obtained for each treated field included patient number, modality, monitor units delivered, gantry angle, and time. D...

During a course of fractionated radiation therapy and between the fractions the tissues of the human body may move relative to some reference location in which the radiation therapy was planned. This has been known for over a century and simple 'coping mechanisms' (margins) have been used to approximately compensate. Since the introduction of highly accurate conformal radiation therapy and inte...

The new era of hybrid MRI and linear accelerator machines, including the MR-linac currently being installed in the University Medical Center Utrecht (Utrecht, The Netherlands), will be able to provide the actual anatomy and real-time anatomy changes of the patient's target(s) and organ(s) at risk (OARs) during radiation delivery. In order to be able to take advantage of this input, a new genera...