The everyday lives of contemporary youths are awash with drugs to boost pleasure, moods, sexual performance, vitality, appearance and health. This paper examines pervasive practices of chemical 'self-maximization' from the perspectives of youths themselves. The research for this paper was conducted among male, female and transgender (male to female, so-called waria) sex workers in Makassar, Ind...

Drug nanoparticle formulation using ascorbic acid derivatives and its therapeutic uses have recently been introduced. Hydrophilic ascorbic acid derivatives such as ascorbyl glycoside have been used not only as antioxidants but also as food and pharmaceutical excipients. In addition to drug solubilization, drug nanoparticle formation was observed using ascorbyl glycoside. Hydrophobic ascorbic ac...

Drug supply shortages are common in health systems due to manufacturing and other delays. Frequently, shortages are successfully addressed through conservation and redistribution efforts, with limited impact on patient care. However, when Sandoz Canada Inc. announced in February 2012 that it was reducing production of a number of generic injectable drugs at its Quebec facility, the scope and ma...

BACKGROUND This meta-analysis of randomized controlled trials aimed to examine the advantages of long-acting injectable antipsychotics over placebo or oral medications regarding efficacy and safety for patients with bipolar disorder. METHODS Two categorical meta-analyses of randomized controlled trials were performed to compare study-defined relapse rate (primary), discontinuation rates, and ...

The modern era has witnessed development of alternate and successful routes of drug delivery system i.e. Transdermal Drug Delivery System (TDDS). In a broad sense, it includes all topically administered drug formulations intended to deliver the active ingredient into the general circulation. Increasing prevalence of diabetes is presently pushing strong demand for novel drug delivery devices. Mo...

Objective: Primary care, which is often the first level of contact for patients with various communicable diseases (CDs) and noncommunicable (NCDs), might exhibit patterns injectable drug utilization different from hospitals. We aimed to examine injection prescribing adults CD or NCD in primary care. Methods: In this retrospective study, single-diagnosis drug-containing prescription data Family...

Injectable polymer microparticles with the ability to carry and release pharmacologically active agents are attracting more interest. This study is focused on chemical synthesis, characterization, preliminary exploration of utility a new type injectable drug-releasing microparticle. The particles feature combination structural physico-chemical properties: (i) their geometry deviates from spheri...