inhalation delivery of aerosolized antibacterials is preferred over conventional methods of delivery for targeting lung infection. the present study is concerned with the development and characterization of a novel, spray dried, aerosolized, chitosan polyelectrolyte complex (pec) based microparticles containing antibacterials for the treatment of lung infections.chitosan polyelectrolyte complex...

the present study deals with the formulation and evaluation of chitosan nanoparticles containing donepezil hydrochloride for the targeted delivery to the brain. nanoparticles were prepared by ionic gelation method using sodium tripolyphos-phate (tpp) as a cross linking agent followed by sonication. nanoparticles were obtained in the average size ranging from 116.8 to 227.5 nm. particle morpholo...

abstractthe aim of the present study was to formulate poly (lactide-co-glycolide) (plga) nanoparticles loaded with 18-β-glycyrrhetinic acid (gla) with appropriate physicochemical properties and antimicrobial activity. gla loaded plga nanoparticles were prepared with different drug to polymer ratios, acetone contents and sonication times and the antibacterial activity of the developed nanopartic...

in the present study, floating drug delivery beads (fdds) were prepared with sodium alginate/ starch blend as a matrix, sodium hydrogen carbonate as a pore forming agent, methyl cellulose as a binder and barium chloride solution as a hardening agent. in order to prepare the beads with different porosity and morphology the ratio between pore forming agent to polymer blend and ratio of the consti...