The aminoglycosides paromomycin and neomycin were examined in Escherichia coli cells for an inhibitory effect on 30S ribosomal subunit assembly. Both compounds inhibited the growth rate, viable cell number, and protein synthesis rate with similar 50% inhibitory concentrations. Each drug also showed a concentration-dependent inhibition of 30S subunit formation. The inhibitory effect on 30S parti...

the aim of this paper was to investigate the antibacterial potential of kelussia odoratissima mozff extract against gram-negative and gram-positive bacteria. karafs-ekoohi with the scientific name of kelussia odoratissima is an iranian endemic edible plant in the middle region of iran with enormous use as food, spice and medicinal herb . the antibacterial effect of the extracts was investigated...

results the combination of bismuth ethanedithiol with ciprofloxacin showed synergistic inhibitory effect on the p. aeruginosa biofilm formation. the combination of bismuth ethanedithiol ciprofloxacin, ceftazidime and imipenem showed synergistic inhibitory effects on the biofilm formation. furthermore, the combination of bismuth ethanedithiol, imipenem and ceftazidime did not show any synergisti...