Objective(s):This study was carried out to investigate the effects of COX-2 selective inhibitor (Celecoxib) or non-selective COX inhibitor (Ibuprofen) on gastrointestinal motility. Materials and Methods: The rats were randomly divided into five groups including: intact, sham, traumatic brain injury (TBI) group (intact rats under TBI), Celecoxib group (10 mg/kg), Ibuprofen group (10 mg/kg). Rats...

In this study, we aimed to investigate the peripheral antinociception effects of specificphosphodiesterase 5 (PDE-5) inhibitor vardenafil on carrageenan-induced nociception in rats,and the role of calcium besides the L-arginine- nitric oxide (NO)- cyclic guanosine monophophate(cGMP) pathway in these effects. Hyperalgesia was induced by the intraplantar injection of 0.1mL fresh carrageenan solut...

Inhibitory effect of extracts from three date varieties namely khalt (kha), Lassiane (La) and Tadmamt (Td)), and the mixture of date varieties as environmentally friendly corrosion inhibitor for carbon steel in 1M HCl is studied by means of electrochemical tests such as electrochemical impedance spectroscopy (EIS), and Tafel polarization. It's been obtained that in 1.0 M HCl solution the date e...

The idea of smart corrosion inhibition is basis on either inhibitor consumption where it is needed or reducing harmful matrix interaction with it. In addition, applying corrosion inhibitor in a coating causes many problems such as loss of inhibition capability, coating degradation, or both. A useful technique to overcome this problem is applying of inert host systems of nanometer dimensions as ...

The corrosion inhibition potential and efficacy of 2-hydropyrimidine-2-thione derivative on mildsteel in 0.5 M sulfuric acid solution was investigated using electrochemical polarization and FTIRspectroscopic techniques. In addition, docking studies were carried out as theoretical investigationof adsorption inhibitor on iron surface. The results of polarization studies indicate...

In this paper, the effect of penicillin G benzathine (PGB) drug as a green corrosion inhibitor on mild steel in 1.0 M hydrochloric acid solution has been investigated using potentiodynamic polarization and electrochemical impedance spectroscopy (EIS) techniques. The inhibition efficiency (IE) was found to increase with increasing inhibitor concentration. Potentiodynamic polarization measure...

Onion (Allium Cepa) contains high levels of flavonoids. Although there are many studies indicating the inhibitory effects of flavonoids on xanthine oxidase, there is no report on the effect of onion on this enzyme. Therefore, in the present study, the inhibitory effects of onion on xanthine oxidase are investigated. Fresh filtered juice of onion was prepared and its inhibitory effect on guine...

Background: Hemophilia B is a bleeding disorder with a recessive X-linked inheritance pattern, in which the infected individuals have low levels of factor IX in their plasma. Affected individuals may have bleeding episodes after trauma or spontaneously considering the plasma level of factor IX. In order to prevent these episodes and to control bleeding, they should use coagulation factor concen...

An unbounded number of events exist beneath the intricacy of each particular hematologic malignancy, prompting the tumor cells into an unrestrained proliferation and invasion. Aberrant expression of cyclin-dependent kinases (CDKs) is one of these events which disrupts regulation of cell cycle and subsequently, results in cancer progression. In this study, we surveyed the repressive impact of mu...