نتایج جستجو برای: influenza a virus

تعداد نتایج: 13592096  

2013
Mingjun Zhao Qingtao Liu Qing Sun Wenjun Zhang Guo Zhao Min Gu Xiaoquan Wang Shunlin Hu Xiaowen Liu Xiufan Liu

In this study, the complete genomic sequence of a novel reassortant H9N2 avian influenza virus (AIV) from domestic ducks in eastern China was reported. Phylogenetic analysis showed that seven of the eight genes were all highly homologous to the chicken-origin H9N2 viruses, whereas the PB2 gene was homologous to the human-origin H1N1 virus, which suggested that domestic ducks might play a key ro...

2010
Risa Indriani Gina Samaan Anita Gultom Leo Loth Sri Indryani Rma Adjid Ni Luh Putu Indi Dharmayanti John Weaver Elizabeth Mumford Kamalini Lokuge Paul M. Kelly

To identify environmental sites commonly contaminated by avian influenza virus A (H5N1) in live-bird markets in Indonesia, we investigated 83 markets in 3 provinces in Indonesia. At each market, samples were collected from up to 27 poultry-related sites to assess the extent of contamination. Samples were tested by using real-time reverse transcription-PCR and virus isolation. A questionnaire wa...

F Behzadian , F Fotouhi-Chahooki , J Fallah , Z Salmani ,

Background and Aims: Virus-like particles (VLPs) have been suggested to be a promising recombinant vaccine approach. Several studies have reported that the influenza VLPs produced in insect cells is an effective vaccine candidate. Due to crucial role of matrix M1 protein in assembly and budding of Influenza particles, in all VLPs structures, M1 protein have been considered as a main component. ...

Background: The flu is a severe and fatal disease with a potential for widespread outbreaks. To reduce the social and economic costs of the disease, vaccination of the entire population and the population at risk is effective. Since every region has a sub-type of influenza virus is endemic, it is necessary to identify the species of native studies done in each area. Methods: In this study, a...

2014
Candice Schmidt Samuel Paulo Cibulski Ana Paula Muterle Varela Camila Mengue Scheffer Adrieli Wendlant Fabiana Quoos Mayer Laura Lopes de Almeida Ana Cláudia Franco Paulo Michel Roehe

In this study, the full-genome sequence of a reassortant H1N2 swine influenza virus is reported. The isolate has the hemagglutinin (HA) and neuraminidase (NA) genes from human lineage (H1-δ cluster and N2), and the internal genes (polymerase basic 1 [PB1], polymerase basic 2 [PB2], polymerase acidic [PA], nucleoprotein [NP], matrix [M], and nonstructural [NS]) are derived from human 2009 pandem...

Journal: :Journal of virology 2001
Y Yao L J Mingay J W McCauley W S Barclay

Reverse genetics was used to analyze the host range of two avian influenza viruses which differ in their ability to replicate in mouse and human cells in culture. Engineered viruses carrying sequences encoding amino acids 362 to 581 of PB2 from a host range variant productively infect mouse and human cells.

Journal: :Antiviral therapy 2005
Frederick Hayden Alexander Klimov Masato Tashiro Alan Hay Amold Monto Jennifer McKimm-Breschkin Catherine Macken Alan Hampson Robert G Webster Michèle Amyard Maria Zambon

The emerging epidemic of H5N1 avian influenza virus with spillover into the human population in Asia has provoked intense concern globally about the potential of these particularly pathogenic viruses to evolve with the capacity for human-to-human transmission with a consequent pandemic. The availability of antiviral drugs with activity against influenza A viruses and the recognition of drug-res...

Journal: :Emerging Infectious Diseases 2009
Rapeepan Dejpichai Yongjua Laosiritaworn Pilaipan Phuthavathana Timothy M. Uyeki Michael O’Reilly Nattaphon Yampikulsakul Sumreung Phurahong Phisanu Poorak Jarunee Prasertsopon Rumporn Kularb Kannika Nateerom Narumol Sawanpanyalert Chuleeporn Jiraphongsa

In 2005, we assessed the seroprevalence of neutralizing antibodies to avian influenza virus A (H5N1) among 901 residents of 4 villages in Thailand where at least 1 confirmed human case of influenza (H5N1) had occurred during 2004. Although 68.1% of survey participants (median age 40 years) were exposed to backyard poultry and 25.7% were exposed to sick or dead chickens, all participants were se...

Journal: :Science 2009
Yang Yang Jonathan D Sugimoto M Elizabeth Halloran Nicole E Basta Dennis L Chao Laura Matrajt Gail Potter Eben Kenah Ira M Longini

Pandemic influenza A (H1N1) 2009 (pandemic H1N1) is spreading throughout the planet. It has become the dominant strain in the Southern Hemisphere, where the influenza season has now ended. Here, on the basis of reported case clusters in the United States, we estimated the household secondary attack rate for pandemic H1N1 to be 27.3% [95% confidence interval (CI) from 12.2% to 50.5%]. From a sch...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2000
Y P Lin M Shaw V Gregory K Cameron W Lim A Klimov K Subbarao Y Guan S Krauss K Shortridge R Webster N Cox A Hay

In 1997, 18 cases of influenza in Hong Kong (bird flu) caused by a novel H5N1 (chicken) virus resulted in the deaths of six individuals and once again raised the specter of a potentially devastating influenza pandemic. Slaughter of the poultry in the live bird markets removed the source of infection and no further human cases of H5N1 infection have occurred. In March 1999, however, a new pandem...

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