Interleukin-2 (IL-2) is a cytokine centrally involved in the regulation of immune tolerance and activation by its effects on CD4+ T regulatory (Treg) cells and cytotoxic effector lymphocytes, respectively. Due to these properties IL-2 immunotherapy has been used, as low-dose IL-2, in the treatment of autoimmune and chronic-inflammatory disorders; conversely, at high doses, IL-2 has shown effica...

BACKGROUND There remains the need for more effective therapeutic options to treat acne vulgaris. Interest in light-based acne treatments has increased, but few randomized, controlled clinical trials assessing the value of photodynamic therapy (PDT) for acne have been reported. AIMS We sought to examine the efficacy of PDT using 5-aminolevulinic acid (ALA) and pulsed dye laser therapy in the t...

INTRODUCTION Acute epididymo-orchitis (AEO) is an acute inflammatory disease of the epididymis and ipsilateral testis. Treatment should be started immediately after diagnosis and includes antibiotics, analgesics, and, if necessary, surgery. MATERIALS AND METHODS After AEO diagnosis, patients were treated conservatively with analgesics and antibiotics. If no clinical improvement was observed w...

background: the pistachio is a nut produced by about 20 species of shrub. present-day studies show the health benefits of pistachio in preventing or treating diseases such as diabetes, cardiovascular diseases (cvds), cancer, multiple sclerosis (ms), and erectile dysfunction. materials and methods: medline / pubmed, and google scholar databases were searched using the keywords of pistacia vera, ...

rheumatoid arthritis (ra) is an inflammatory progressive disease which in the absence of appropriate treatment can lead to joint destruction and disability. prognosis of ra may be predicted based on the presence of some clinical and laboratory evidences.new criteria for classification of ra provides opportunity for earlier treatment. initiation of treatment particularly by combination of dmards...

objective: solenostemon monostachyus is used in traditional medicine for the treatment of various ailments such as ulcer, hypertension, pains and inflammatory diseases. evaluation of anti-inflammatory and analgesic activities of s. monostachyus aerial parts was carried out to ascertain its uses in traditional medicine. materials and methods: the aerial parts of s. monostachyus was cold extracte...

the leukotrienes and prostaglandins are biologically active metabolites derived from arachidonic acid. the leukotrienes have a role in inflammatory diseases such as allergic rhinitis, inflammatory bowel disease and asthma. montelukast, a cysteinyl leukotriene receptor antagonist, is claimed to be effective in asthma. the present study aimed to assess the role of cysteinyl leukotriene receptor a...

Meloxicam is a non steroidal anti-inflammatory drug, used in the treatment of rheumatoid arthritis and oestoarthritis. It is practically insoluble in water leading to poor dissolution, variations in bioavailability and gastric irritation on oral administration. In order to modulate its gastric side effect and to increase aqueous solubility, physical mixture and solid dispersion of the drug were...