Hydroxydihydrocarvone (HC) is a synthetic intermediate obtained by hydration of the natural compound (R)-(-)-carvone. The aim of the present study was to investigate the possible anti-inflammatory activity of orally administered HC. Toxicity, motor coordination, tail immersion test, as well as carrageenan-induced paw edema and myeloperoxidase (MPO) activity or peritonitis were all evaluated in ...

physalis angulata is a medicinal plant used for the treatment of malaria, ulcer, pains and other diverse ailments. the present study evaluated the analgesic and anti-inflammatory activity of methanolic leaf extract of the plant. acetic acid-induced abdominal contraction or writhing analgesic models in swiss albino mice (13-23g) were used for studying analgesic activity of the leaf extract. 200,...

Objective(s): In the present study, we investigated the potential anti-nociceptive activity and acute anti-inflammatory effect of a synthetic quinoline compound (2-(4-Methoxyphenyl)benzo[h]quinoline-4-carboxylic acid, QC), possessing structural elements of both naproxen and tomoxiprole drugs. Materials and Methods: The anti-nociceptive activity of QC was evaluated using chemical- and thermal-in...

1. Assistant Professor of Pharmacology, Bahria University Medical & Dental College, Karachi. 2. Assistant Professor of Pharmacology, Bahria University Medical & Dental College, Karachi. 3. Professor of pharmacology, United Medical & Dental College, Karachi 4. Professor of Pharmacology, Bahria University Medical & Dental College, Karachi. ABSTRACT... Objective: To evaluate anti-inflammatory acti...

In the present work we carried out a phytochemical and biological investigation on three endemic Hypericum species, i.e. Hypericum thymbrifolium, Hypericum spectabile and Hypericum pseudolaeve from Anatolia in order to discover new sources of natural compounds for the treatment of inflammatory and neurodegenerative disorders. HPLC-DAD analysis indicated that two naphthodianthrones (pseudohyperi...

The present study was designed to assess the cytotoxicity, anti-inflammatory and analgesic properties of methanol extract of Woodfordia fruticosa flowers. Cytotoxic activity of methanol extract of Woodfordia fruticosa flowers was tested using Artemia salina (Brine shrimp) bioassay. Two doses (400 and 600 mg/Kg) were evaluated for the anti-inflammatory activity against the carrageenan, histamine...