One of the most profound and philosophically captivating foci modern astronomy is studies Earth-like exoplanets in search life Universe. The paradigm-shifting investigation described here calls for a new type space telescope that redefines available light-collecting area space, far beyond what currently possible with 6.5 m diameter James Webb Space Telescope. Nautilus Observatory, which enabled...

In their classic paper on the identification of the transforming principle of Rous sarcoma virus (RSV) published 1970 in PNAS (1), Peter Duesberg at the University of California, Berkeley, and Peter Vogt, then at the University of Washington, Seattle, drew a seemingly simple yet groundbreaking conclusion. When they analyzed the genomic RNAs of transforming, acutely oncogenic RSV and of transfor...

Thanks to recent middleware developments including technology advancements, standardization initiatives, and new innovative approaches to building embedded systems, OEMs and system integrators no longer need to think in terms of trade-offs when developing their systems. With COTS middleware, assuming functionality will come at a higher price or that a highly compatible system will severely limi...

Glioblastomas are the most malignant gliomas with median survival times of only 15 months despite modern therapies. All standard treatments are palliative. Pathogenetic factors are diverse, hence, stratified treatment plans are warranted considering the molecular heterogeneity among these tumors. However, most patients are treated with "one fits all" standard therapies, many of them with minor ...

There have been many new and exciting developments in mass spectrometer systems in recent years. Many of these developments are being driven by challenges presented by molecular biology. The activity is fueled by resources being devoted to drug development, for example, and other medically and biologically related activities. Progress in these applications will be accelerated by improved sensit...

Objectives: Fibro-osseous lesions of the craniofacial complex comprise of a diverse, interesting and challenging group of conditions that pose difficulties in classification and treatment. The two most confused benign fibro-osseous lesions are fibrous dysplasia and ossifying fibroma. Sometimes, the classic clinical, radiologic or pathologic features of fibrous dysplasia or ossifying fibroma may...