نتایج جستجو برای: infection process including spore germination

تعداد نتایج: 2542389  

Journal: :Journal of applied microbiology 2009
B Setlow L Peng C A Loshon Y-Q Li G Christie P Setlow

AIMS To determine roles of cortex lytic enzymes (CLEs) in Bacillus megaterium spore germination. METHODS AND RESULTS Genes for B. megaterium CLEs CwlJ and SleB were inactivated and effects of loss of one or both on germination were assessed. Loss of CwlJ or SleB did not prevent completion of germination with agents that activate the spore's germinant receptors, but loss of CwlJ slowed the rel...

Journal: :Journal of applied microbiology 2008
V Broussolle F Gauillard C Nguyen-The F Carlin

AIMS Our aim was to assess the diversity of the nutrient germination response of Bacillus cereus spores. METHODS AND RESULTS B. cereus spore germination was monitored by decrease in optical density using a Bioscreen C analyser in response to the major germinant substances inosine and l-alanine. Spores of a set of 12 strains taken to illustrate the diversity of the B. cereus group showed rangi...

Journal: :Journal of bacteriology 1954
P C FITZ-JAMES

In a separate paper, the changes in the P fractions of bacterial spores (luring geimination weere correlated with the morphological changes which took place at the same time. Germination has heen defined as the over-all period, some 50 to 60 min, extendling from the resting state of the "mononucleate" spore to the vegetative or "binucleate" cell. Thick suspensions (109 spores/ml) of synchronous...

Journal: :Antimicrobial agents and chemotherapy 2010
Zadkiel Alvarez Kyungae Lee Ernesto Abel-Santos

Bacillus anthracis, the etiological agent of anthrax, has a dormant stage in its life cycle known as the endospore. When conditions become favorable, spores germinate and transform into vegetative bacteria. In inhalational anthrax, the most fatal manifestation of the disease, spores enter the organism through the respiratory tract and germinate in phagosomes of alveolar macrophages. Germinated ...

Journal: :Journal of bacteriology 2008
Patricia L Pelczar Peter Setlow

GerD of Bacillus subtilis is a protein essential for normal spore germination with either L-alanine or a mixture of L-asparagine, D-glucose, D-fructose, and potassium ions. GerD's amino acid sequence suggests that it may be a lipoprotein, indicating a likely location in a membrane. Location in the spore's outer membrane seems unlikely, since removal of this membrane does not result in a gerD sp...

Journal: :BMC Pharmacology 2006
Mark Evan Goldman Lynne Cregar Dominique Nguyen Ondrej Simo Sean O'Malley Tom Humphreys

BACKGROUND Anthrax is a human disease that results from infection by the bacteria, Bacillus anthracis and has recently been used as a bioterrorist agent. Historically, this disease was associated with Bacillus spore exposure from wool or animal carcasses. While current vaccine approaches (targeted against the protective antigen) are effective for prophylaxis, multiple doses must be injected. Co...

Journal: :Journal of bacteriology 1980
D Eaton J C Ensign

Initiation of germination of heat-activated Streptomyces viridochromogenes spore occurs in media containing only calcium ions and organic buffer. The calcium-induced initiation of germination was accompanied by a decrease in absorbance of the spore suspension, an increased rate of endogenous metabolism, the loss of spore carbon, and the loss of heat resistance. Calcium amounts to 0.28% of the d...

Journal: :Journal of proteome research 2010
Boqiang Li Tongfei Lai Guozheng Qin Shiping Tian

Spore germination is the first step for fungal pathogens to infect host plants. The pH value, as one of the most important environmental parameters, has critical influence on spore germination. In this study, effects of ambient pH on spore germination were determined by culturing spores of Penicillium expansum in medium with pH values at 2.0, 5.0 and 8.0, and involved mechanisms were further in...

2015
Kelly A. Fimlaid Owen Jensen M. Lauren Donnelly Michael B. Francis Joseph A. Sorg Aimee Shen Theresa M. Koehler

Clostridium difficile is a Gram-positive spore-forming pathogen and a leading cause of nosocomial diarrhea. C. difficile infections are transmitted when ingested spores germinate in the gastrointestinal tract and transform into vegetative cells. Germination begins when the germinant receptor CspC detects bile salts in the gut. CspC is a subtilisin-like serine pseudoprotease that activates the r...

Journal: :Journal of bacteriology 2011
Marc Liggins Norma Ramirez Natiera Magnuson Ernesto Abel-Santos

Clostridium sordellii and Clostridium difficile are closely related anaerobic Gram-positive, spore-forming human pathogens. C. sordellii and C. difficile form spores that are believed to be the infectious form of these bacteria. These spores return to toxin-producing vegetative cells upon binding to small molecule germinants. The endogenous compounds that regulate clostridial spore germination ...

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