objective: to correlate serum estrogen levels with cognitive functions calculated objectively as per mini mental state examination (mmse) in the females in reproductive age group and those attaining menopause. materials and methods: this study was conducted in christian medical college and hospital, ludhiana, punjab, india. 150 subjects (100 postmenopausal females and 50 regularly menstruating ...

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that affects regions of the brain that control cognition, memory, language, speech and awareness to one’s physical surroundings. The pathological initiation and progression of AD is highly complex and its prevalence is on the rise. In his study, Alzheimer's disease was induced with single injection of amyloid-β (Aβ) peptides (...

Background: Identification of regional pattern of poisoning is essential for health care authorities for proper planning on prevention programs and optimized management of antidote stockpiles. This study was designed to evaluate one-year epidemiologic pattern of acute poisoning cases treated at a tertiary care hospital in Thrissur, India. Methods: In this retrospective cross sectional study, me...

Chronic pain is a prevalent and debilitating condition, conveying immense human burden. Suffering from chronic pain is not only caused by painful symptomatology, but also through a wide range of psychopathological and physical consequences, including depression and anxiety disorders, impaired sleep and cognition, cardiovascular morbidity and impaired sexual function, all contributing to diminis...

Assisted Cognition systems provide active cognitive aids for people with reduced memory and problem-solving abilities due to Alzheimer’s Disease or other disorders. Two concrete examples of the Assisted Cognition systems we are developing are an ACTIVITY COMPASS that helps reduce spatial disorientation both inside and outside the home, and an ADL PROMPTER that helps patients carry out multi-ste...

Alzheimer’s disease (AD) is a disorder of synaptic function and neuronal degeneration characterized by decline in memory and cognition as well as changes of personality. Brain-Derived Neurotrophic Factor (BDNF) is a major modulator of synaptic plasticity and is an acknowledged pharmacological target for the treatment of a range of neurological disorders including AD. Attempts to supply BDNF exo...