According to international epidemiological studies, the total number of reported cases cardiovascular diseases (CVD) almost doubled from 1990 2019, reaching 523 million and deaths CVD in 2019 increased by more than 1.5 times (18,6 million). Coronary artery disease (CAD) stroke are main contributors these unfavorable trends. The registered coronary heart amounted 197 million, caused exceeded hal...

introduction: heart failure is a major hazard for public health. despite recent advance in medical therapy, there is not enough information on the outcome of off-pump coronary artery bypass (opcab) and medical therapy on the patients with severe ventricular dysfunction and triple-vessel (cad). this study aimed to compare treatment outcomes and mortality rate in patients undergoing off-pump coro...

background : the short form health survey (sf-36) and who quality of life-bref (whoqol-bref) questionnaires are two common tools to assess changes in quality of life (qol) over the course of treatment, especially in patients with coronary artery disease (cad). however, the value of these two instruments among cad patients has not been studied and compared. the objective of the present study was...

IntRoductIon Coronary computed tomographic angiography (CCTA) as a noninvasive diagnostic technique for the evaluation of coronary anatomy is widely used clinically. Its advantages include high sensitivity and specificity for the diagnosis of present of coronary artery lesions and lesion characteristics, short scan time, low patient radiation exposure, and acceptable to patients. The sensitivit...

background: coronary artery disease (cad) is a multifactorial and heterogenic disease. recently, genome-wide association studies have reported that rs1333040 (c/t) and rs1004638 (a/t) single nucleotide polymorphisms (snps) in the 9p21 locus have very strong association with cad. this study aimed to examine these associations in southwest of iran. methods: blood samples were collected from 200 c...

Atherosclerosis is one of the most important coronary artery disease (CAD) caused by lipid accumulation, hypertension, smoking, and many other factors such as environmental and genetic factors. It has been recorded that genetic variations in rs10757278 and rs1333049 are correlated with CAD. In the present study, 100 blood samples were collected (50 CAD patients and 50 appeared to be healthy con...

background: the study of the association between genotype and phenotype is of great importance for the prediction of many diseases and pathophysiological conditions. the relationship between angiotensin-converting enzyme (ace) gene insertion/ deletion (i/d) polymorphism and pathological processes such as coronary artery disease (cad) has been investigated previously with discordant results. thi...

Left bundle branch block (LBBB) poses some restriction on coronary artery disease (CAD) diagnosis with noninvasive diagnostic modalities. Objectives: Evaluating the role of 2-D speckle tracking echocardiography (STE) in CAD patients LBBB.