Disulfiram (DS) has an excellent anti-viral activity; however, its low water-solubility and first-pass metabolism are limiting clinical applications. Cyclodextrins (CDs) have been used as solubility enhancers carriers of DS proposed for inhalation to treat SARS-CoV-19. Two types CDs (hydroxypropyl β-cyclodextrin sulfobutyl ether β-cyclodextrin) were form inclusion complexes wi...