نتایج جستجو برای: in vivo performance

تعداد نتایج: 17161660  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور استان تهران - دانشکده علوم 1388

یکی از دلایل آمار بسیار بالای موارد ابتلا و مرگ و میر ناشی از بیماری مالاریا مقاومت انگل پلاسمودیوم به داروهای کلاسیک مانند کلروکین بوده و بنابراین تهیه ی داروهای جدید و تعیین هدف های نوین دارویی در این بیماری بسیار حائز اهمیت می باشد. یکی از ترکیبات جدید در این زمینه ماده ی رنگی "ائوزین b" می باشد که پیشتر در شرایط in vitro در انگل های مقاوم اثرات ضد مالاریایی خوبی نشان داده است و در این تح...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت دبیر شهید رجایی - دانشکده علوم انسانی و تربیت بدنی 1389

teachers’ beliefs greatly influence their performance in the classroom, their choice of instructional strategies, their way of controlling the class, their dealing with the students, and their general goals and objectives. one of these beliefs is teachers’ sense of efficacy which is viewed as an important construct and has shown to be positively correlated with students’ achievement (ross, 1992...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - پژوهشکده مهندسی فرایند 1395

abstract: mineral scaling in oil and gas production equipment is one of the most important problem that occurs while water injection and it has been recognized to be a major operational problem. the incompatibility between injected and formation waters may result in inorganic scale precipitation in the equipment and reservoir and then reduction of oil production rate and water injection rate. ...

پایان نامه :0 1374

in fact this study is concerned with the relationship between the variation in thematice structure and the comprehension of spoken language. so the study focused on the following questions: 1. is there any relationship between thematic structure and the comprehension of spoken language? 2. which of the themes would have greated thematic force and be easier for the subjects to comprehend? accord...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تبریز - دانشکده ادبیات و زبانهای خارجی 1393

abstract this quasi-experimental study was aimed at examining the impact of storyline complexity on the grammatical accuracy and complexity of advanced and intermediate efl learners. a total of 65 advanced and intermediate efl learners were selected from iran language institute (ili). an intact group including 35 intermediate participants and another intact group with 30 advanced participants ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده علوم پایه 1390

علارغم پیشرفت های اخیر در زمینه درمان سرطان، این بیماری همچنان دومین علت مرگ و میر بعد از بیماری های قلبی-عروقی محسوب می شود. از سوی دیگر، نگرانی های ناشی از عوارض جانبی داروهای رایج امروزی و هزینه های هنگفت تهیه آنها باعث شده است تا در سال های اخیر دانشمندان توجه خود را به طب سنتی به عنوان منبعی غنی از ترکیبات شیمیائی با پتانسیل بالای داروئی و از همه مهمتر فاقد اثرات جانبی روی سلول های نرمال م...

Journal: :iranian journal of public health 0
malihe zahiri mehdi mohebali mahnaz khanavi mousa sahebgharani abedin saghafipour jamileh esmaeili

background: we evaluated the effect of the ethanolic extract of scrophularia striata on the iranian strain of leishmania major (mrho/ir/75/er) both in vitro and in vivo conditions methods: the effective dose (ed) of ethanolic extract of s. striata were determined using  mtt assay  on the growth of promastigote forms of  l. major in axenic culture media. then, the ed 50 of  s. striata on mice pe...

Journal: :physiology and pharmacology 0
valiollah hajhashemi dept. pharmacology and isfahan pharmaceutical research center, school of pharmacy, isfahan univ. med. sci., isfahan. mohsen minaiyan mahdi saberian-boroojeni

introduction: urine morphine test, in several countries is the most primarily available qualitative test for detecting opioid abusers. since the users of illicit drugs attempt to defeat urine tests and there are also plenty of claims that usage of hd (high dose) contraceptive pills can result in false-negative results, we decided to design the present study to investigate the probable in vitro ...

Journal: :iranian journal of pharmaceutical research 0
matylda resztak department of physical pharmacy and pharmacokinetics, k. marcinkowski university of medical sciences, święcickiego 6 st., 60-781 poznań, poland tadeusz władysław hermann department of physical pharmacy and pharmacokinetics, k. marcinkowski university of medical sciences, poland wiesław sawicki department of pharmaceutical technology, medical university of gdańsk, poland dorota zuzanna danielak department of physical pharmacy and pharmacokinetics, k. marcinkowski university of medical sciences, poland

the objective of the study was to compare pharmacokinetic and pharmacodynamic parameters of gliclazide after administration of immediate (ir) and modified release (mr) tablets. the experiment included rats with both normoglyceamia and streptozocin (stz)-induced hyperglyceamia. several mr formulations were designed and in vitro drug release profile was assessed by a dissolution test. for the fur...

Journal: :journal of biomedical physics and engineering 0
b. j. allan experimental radiation oncology school of medicine university of western sydney, liverpool 2170 nsw australia

background: the fundamental principles of internal targeted alpha therapy for cancer were established many decades ago.the high linear energy transfer (let) of alpha radiation to the targeted cancer cellscauses double strand breaks in dna. at the same time, the short range radiation spares adjacent normal tissues. this targeted approach complements conventional external beam radiotherapy and ch...

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