نتایج جستجو برای: in silico 3d molecular model

تعداد نتایج: 17468448  

Journal: :Nature communications 2012
Joshua A Lerman Daniel R Hyduke Haythem Latif Vasiliy A Portnoy Nathan E Lewis Jeffrey D Orth Alexandra C Schrimpe-Rutledge Richard D Smith Joshua N Adkins Karsten Zengler Bernhard O Palsson

Transcription and translation use raw materials and energy generated metabolically to create the macromolecular machinery responsible for all cellular functions, including metabolism. A biochemically accurate model of molecular biology and metabolism will facilitate comprehensive and quantitative computations of an organism's molecular constitution as a function of genetic and environmental par...

Journal: :Clinical and Research Journal in Internal Medicine 2021

Background:Â Malaria is an endemic disease that can lead to death. control a threatening cause of resistance antimalarial drugs so renewable therapies are needed overcome this disease. The chemical compounds garlic have potential as agents, but the mechanism still unknown. Aim:Â This research will predict compounds' molecular in (Allium sativum) using in-silico method. Methods:Â In-silico metho...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2005
Chioko Nagao Tomoki P Terada Tetsuya Yomo Masaki Sasai

Evolution should have played important roles in determining folding mechanisms and structures of proteins. In this article we discuss how the folding mechanisms had been affected by the early stage of evolution through which the uniqueness of structure had developed. Although the process of such early-time evolution has remained a mystery, a plausible scenario is that the evolution of proteins ...

Journal: :journal of water sciences research 2010
a khosronejad

in the present paper, a 3d numerical model has been applied to predict the flow hydrodynamics around power intakes within the dez dam reservoir. the dez dam is a 203 m high, double arch concrete dam which is constructed by italians in 1962. since then, sedimentation in reservoirhas continued and since the dam does not have bottom outlet, the reservoir bed level is raising by a rate of about 2.5...

2011
Irena Roterman Leszek Konieczny Mateusz Banach Wiktor Jurkowski

The paper presents a model for simulating the protein folding process in silico. The two-step model (which consists of the early stage-ES and the late stage-LS) is verified using two proteins, one of which is treated (according to experimental observations) as the early stage and the second as an example of the LS step. The early stage is based solely on backbone structural preferences, while t...

Journal: :international journal of molecular and cellular medicine 0
behnam alipoor department of biochemistry, faculty of medicine, tehran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences) hamid ghaedi department of medical genetics, faculty of medicine, shahid beheshti university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (shahid beheshti university of medical sciences) mir davood omrani department of medical genetics, faculty of medicine, shahid beheshti university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (shahid beheshti university of medical sciences) milad bastami department of medical genetics, faculty of medicine, shahid beheshti university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (shahid beheshti university of medical sciences) reza meshkani department of biochemistry, faculty of medicine, tehran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences) taghi golmohammadi department of biochemistry, faculty of medicine, tehran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences)

it has been suggested that single nucleotide polymorphisms (snps) in genes involved in toll-like receptors (tlrs) pathway may exhibit broad effects on function of this network and might contribute to a range of human diseases. however, the extent to which these variations affect tlr signaling is not well understood. in this study, we adopted a bioinformatics approach to predict the consequences...

ژورنال: :genetics in the 3rd millennium 0
نجف الهیاری فرد najaf allahyari fard زرین مینوچهر zarrin minuchehr امیر موسوی amir mousavi

موجودات تراریخته اهمیت، کاربرد و گستره وسیعی در زیست فناوری دارند. گیاهان تراریخته در دهه اخیر به منظور تولید مواد غذایی و مصارف صنعتی رشد و توسعه قابل توجهی داشته اند. چراکه استفاده از گیاهان و محصولات تراریخته با توجه به محدودیتهای افزایش سطح زیر کشت، راه حلی کلیدی پاسخ به تقاضای روزافزون غذا در جهان است. از اینرو ایمنی مصرف محصولات تراریخته یکی از ضروریات مهم به شمار می رود. یکی از مهم ترین ...

The advent of 3D printers has been embraced globally within few years of its emergence. The surge in the acceptability of rapid manufacturing RM technology can be attributed to the depletion and cost of natural resources, waste reduction and sustainability criterion of manufactured parts. This rapidly evolving 3D printing technologies is predicted to grow exponentially especially for the manufa...

Upper Gotvand dam is constructed on the Karun River located in the south west of Iran. In this paper, 2D and 3D models of the dam together with the foundation and abutments were constructed and several seepage analyses were carried out. Then the gypsum veins scattered throughout the foundation ground and also the seepage pattern were included in the models, hence the dissolution law of gypsum, ...

Shui-Ping Yang Wei-Qi Liu Xian Yang, Xue Zhang

In the present study, the antimicrobial tests of patchouli oil were studied by using molecular docking technology and antimicrobial test in vitro. Five biological macromolecule enzymes, required by the bacteria in the process of biosynthesis were selected as target molecules. Five antibiotics benzylpenicillin, sulfadiazine, trimethoprim, rifampicin and ciprofloxacin, which are generally acknowle...

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