Metabolite carrier proteins of the mitochondrial inner membrane share homology in their transmembrane domains, which also carries their targeting information. In addition, some carriers have cleavable presequences which are not essential for targeting, but have some other function before import. The cytosolic chaperones Hsc70 (heat-shock cognate 70) and Hsp90 (heat-shock protein 90) complex wit...

rice comes second after wheat in iran`s food consumption economy. however iran is one of the greatest rice importer countries all over the world because of its rising population and recent growth in gdp. this paper presents an analysis of cointegration test between rice import and it`s economic factors over the period 1990-2011, employing engle-granger model. at first, dickey-fuller test shows ...

rice comes second after wheat in iran`s food consumption economy. however iran is one of the greatest rice importer countries all over the world because of its rising population and recent growth in gdp. this paper presents an analysis of cointegration test between rice import and it`s economic factors over the period 1990-2011, employing engle-granger model. at first, dickey-fuller test shows ...

foreign trade of any country is considered as one of the major economic sectors of that society as far as some refer to trade as the “engine of growth”. foreign exchange rate and its volatilities is one of the effective factors determining foreign trade. the present paper deals with the impact of real exchange rate uncertainty on imports in iran during 1979-2009. in this respect, first, among v...

uclear import is slowed by too much of a good thing. So says a new systems model of nuclear import from Riddick and Macara (page 1027), which predicts that high levels of the cargo carrier Importin-␤ or the RanGEF RCC1 inhibit import. With its simple nucleus-versus-cytoplasm architecture, import is a good candidate for systems analysis. Most of the components have been identified, and biochemic...

Kinetic competition experiments have demonstrated that at least some factors required for the nuclear import of proteins and U snRNPs are distinct. Both import processes require energy, and in the case of protein import, the energy requirement is known to be at least partly met by GTP hydrolysis by the Ran GTPase. We have compared the effects of nonhydrolyzable GTP analogues and two mutant Ran ...

Nucleocytoplasmic trafficking pathways and the status of nuclear pore complex (NPC) components were examined in cells infected with rhinovirus type 14. A variety of shuttling and nonshuttling nuclear proteins, using multiple nuclear import pathways, accumulated in the cytoplasm of cells infected with rhinovirus. An in vitro nuclear import assay with semipermeabilized infected cells confirmed th...

Import of proteins into the nucleus proceeds through nuclear pore complexes and is largely mediated by nuclear transport receptors of the importin β family that use direct RanGTP-binding to regulate the interaction with their cargoes. We investigated nuclear import of the linker histone H1 and found that two receptors, importin β (Impβ) and importin 7 (Imp7, RanBP7), play a critical role in thi...

In counterpoint to export growth, Bangladesh import growth has remained much less strong, despite impressive progress in import liberalization. This study gives an overview of different methodologies related to gravity model analysis in Bangladesh’s import flow. A pooled cross section and time series data were analyzed to incorporate the country specific heterogeneity in country pair trading pa...

Nuclear import of karyophilic proteins is carried out by a variety of mechanisms. We previously showed that two basic helix-loop-helix proteins, NeuroD1 and E47, synergistically affect each other's nuclear import. In this study, we dissected the molecular pathways underlying nuclear import of the NeuroD1/E47 heterodimer. In vitro nuclear import assays indicated that importin α family members ar...