نتایج جستجو برای: immunoprotection

تعداد نتایج: 226  

Journal: :The Journal of infectious diseases 2015
Silvia I Cazorla Marina N Matos Natacha Cerny Carolina Ramirez Andrés Sanchez Alberti Augusto E Bivona Celina Morales Carlos A Guzmán Emilio L Malchiodi

We have reported that attenuated Salmonella (S) carrying plasmids encoding the cysteine protease cruzipain (Cz) protects against Trypanosoma cruzi infection. Here, we determined whether immunoprotection could be improved by the oral coadministration of 3 Salmonella carrying the plasmids that encode the antigens Cz, Tc52, and Tc24. SCz+STc52+STc24-immunized mice presented an increased antibody r...

Journal: :Infection and immunity 1988
J G Olenick R Wolff R K Nauman J McLaughlin

In contrast to the abundance of detailed information on variant-specific surface coat antigens of African trypanosomes, data on possible common or nonvariant antigens within these protozoa are surprisingly limited. In this study, the cellular localization and protective potential of a previously characterized flagellar pocket membrane (FPM) fraction were determined. Immunogold staining of live ...

Journal: :Indian journal of experimental biology 2015
M Parthiban S Senthil Kumar C Balachandran K Kumanan K S Aarthi G Nireesha

Leptospirosis is a bacterial disease caused by bacteria of the genus Leptospira affecting humans and animals. Untreated leptospirosis may result in severe kidney damage, meningitis, liver failure, respiratory distress, and even death. Virulent leptospirosis can rapidly enter kidney fibroblasts and induce a programmed cell death. Thus, it is a challenge for immunologists to develop an effective ...

Journal: :Veterinary research 2004
Antonio Ruiz José Manuel Molina Jorge Francisco González Magnolia María Conde Sergio Martín Yeray Isidro Hernández

Haemonchus cysteine proteases, because of their apparent critical function in worm physiology, are considered important candidates in the immunological control of haemonchosis in sheep. Only limited information is, however, available on the immunoprotective properties of these molecules in goats. In the present study cysteine proteases of Haemonchus contortus adult worms isolated from a goat st...

Journal: :Frontiers in bioscience 2018
Renato Andreotti Poliana Fernanda Giachetto Rodrigo Casquero Cunha

Rhipicephalus (Boophilus) microplus has substantial economic impact on the cattle breeding industry and, chemical control and tick resistance development are the major concern. There is a worldwide search for new options, and control using vaccines has been the main focus nowadays. Studies performed in Brazil found that Bm86-based immunization of bovines reduced the infestation of R. (B.) micro...

Journal: :The Journal of experimental biology 2012
Zuzana Kankova Michal Zeman Monika Okuliarova

The effects of maternal androgens on fitness-related traits of offspring are generally assumed to be epigenetic adaptations to the environment that may be encountered by the next generation. Possible constraints of high yolk androgen transfer are still not understood, although a suppressed immune response in offspring is frequently considered. The aim of our study was to examine the innate immu...

2015
Yun Sun Li Sun Yolande Richard

B cell activating factor (BAFF) is a member of the tumor necrosis factor family that is known to play an important role in B cell activation, proliferation, and differentiation in mammals. However, studies of BAFF in teleosts are very limited and its function, in particular that under in vivo conditions, is essentially unknown. In this study, we conducted in vivo as well as in vitro functional ...

2013
F Chen Q Liu Y Xue YH Huang FY Huang Y Lin GH Tan J Zhou

BACKGROUND Malaria remains a serious public health problem with significant morbidity and mortality. This study was conducted to identify whether ficolin-A could play an active role of against malaria infection. METHODS The function of ficolin-A was analyzed in mouse model. The open reading frame of ficolin-A was cloned from the liver of new born C57BL/6 mice by RT-PCR and then inserted into ...

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