نتایج جستجو برای: immunoinformatics
تعداد نتایج: 321 فیلتر نتایج به سال:
Porcine epidemic diarrhea virus (PEDV), a continuously evolving pathogen, causes severe in piglets with high mortality rates. However, current vaccines cannot provide complete protection against PEDV, so vaccine development is still necessary and urgent. Here, the help of immunoinformatics approaches, we attempted to design multi-epitope named rPMEV prevent control PEDV infection. The epitopes ...
ARTICLE INFO: Article history: Received: 30 September 2014 Received in revised form: 15 October 2014 Accepted: 20 October 2014 Available online: 31 December 2014
The virus surface protein neuraminidase (NA) is a main subtype-specific antigen in influenza type A viruses. Neuraminidase functions as an enzyme to break the bonds between hemagglutinin (HA) and sialic acid to release newly formed viruses from infected cells. In this study, NA genes from the H3N2 subtype virus were sequenced and NA proteins were screened for B-cell epitopes and assessed based ...
Leishmaniasis is a wide-spectrum disease caused by parasites from Leishmania genus. There is no human vaccine available and it is considered by many studies as apotential effective tool for disease control. To discover novel antigens, computational programs have been used in reverse vaccinology strategies. In this work, we developed a validation antigen approach that integrates prediction of B ...
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