Cartilage proteoglycan is thought to be composed of subunits, core proteins with covalently attached sulphated polysaccharide side chains, which form aggregates by non-covalent association with a link protein. The new technique of non-disruptive extraction followed by fractionation in caesium chloride gradients provides a useful means of preparing relatively pure proteoglycan aggregate, subunit...

Primary thyroid lymphomas (PTL) are very rare and account for only 2.5% to 5% of all thyroid malignancies and 1-2% of all extra-nodal malignancies [1]. PTL is more prevalent in females in the sixth to seventh decade of life [2]. The presentation of PTL can be puzzling. PLT may be mistaken for anaplastic thyroid cancer. Immunochemistry is an important part of pathologic differentiation of these ...

F. Slingsby1, X. Shu1, A. Herbert2, M. Lyon3, L. Mackay2, J. Creanor2, D. Uhrin2, P. Barlow2, R. Sim4, A. Wright1. 1MRC Human Genetics Unit, Edinburgh, United Kingdom; 2School of Chemistry and Biological Sciences, University of Edinburgh, Edinburgh Biomolecular NMR Unit, Edinburgh, United Kingdom; 3University of Manchester, Department of Medical Oncology, Manchester, United Kingdom; 4Department...

An association between the complement system and immune complex glomerular disease in humans has long been recognized. In fact, much of our early understanding of the immunochemistry of complement activation developed with the study of acute and chronic glomerulonephritis (1). This manuscript will examine associations between glomerulonephritis and the three complement components encoded within...

The antigenic specificity of Listeria monocytogenes types I, II, III, IVa, and IVb was studied by immunochemical techniques. Immunologically active carbohydrates of the various types were extracted from cell walls and were chemically analyzed. Types I and II contained predominantly glucosamine and rhamnose; type III, galactose, rhamnose, and glucosamine; and types IVa and IVb, glucose and galac...