BACKGROUND Somatic cell nuclear transfer (SCNT) is a promising technique to produce transgenic cloned mammalian, including transgenic goats which may produce Human Lactoferrin (hLF). However, success percentage of SCNT is low, because of gestational and neonatal failure of transgenic embryos. According to the studies on cattle and mice, DNA methylation of some imprinted genes, which plays a vit...

BACKGROUND Assisted reproductive technologies allow to utilize a limited number of fully grown oocytes despite the presence in the ovary of a large pool of meiotically incompetent gametes potentially able to produce live births. In vitro folliculogenesis could be useful to recruit these oocytes by promoting their growth and differentiation. METHODOLOGY/PRINCIPAL FINDINGS In vitro folliculogen...

We have characterized the temporal expression of the insulin-like growth factor (IGF) axis in the transgenic adenocarcinoma of mouse prostate (TRAMP) model as prostate cancer progression in this model closely mimics that observed in the human disease, and the model provides samples representing the earliest stages of prostate cancer that are clinically the most difficult to obtain. We report th...

These notes cover the first part of an introductory course on computational linguistics, also known as MPRI 2-27-1: Logical and computational structures for linguistic modelling. The course is subdivided into two parts: the first, which is the topic of these notes, covers grammars, automata, and logics for syntax modelling, while the second part focuses on logical approaches to semantics. Among...

These notes cover the first part of an introductory course on computational linguistics, also known as MPRI 2-27-1: Logical and computational structures for linguistic modelling. The course is subdivided into two parts: the first, which is the topic of these notes, covers grammars, automata, and logics for syntax modelling, while the second part focuses on logical approaches semantics. Among th...