Uveitis refers to the presence of intraocular inflammation, and as a strict definition compromises the iris and ciliary body anteriorly and the choroid posteriorly (the uvea). Untreated, uveitis can lead to visual loss or blindness. The etiology of uveitis can include both infectious and noninfectious (usually immune-mediated) causes, the latter of which are often mediated predominantly by Th1 ...

Results 12 patients with idiopathic uveitis were enrolled in this study. 10 of them were female and 2 were male. The youngest patient was a 7-year-old child and the oldest was 57. The most common complaints of patients was blurred vision and then eye redness. One patient was heterozygous for Wt/R761H in the MEFV genetic analyses. Genetic analysis of 12 most common MEFV mutations in the patients...

Canine anterior uveitis can be a debilitating, painful, vision-threatening disease. Several local and systemic diseases can cause anterior uveitis. Because the eye is limited in its ability to respond to injury, different diseases produce similar clinical signs, making an etiologic diagnosis difficult but imperative to improve the likelihood of a successful outcome. A thorough history and compl...

PReS-FINAL-2063: Proposed criteria for activity, damage and impact of juvenile idiopathic arthritis associated uveitis: consensus effort from the multinational interdisciplinary working group for uveitis in childhood (MIWGUC) I Foeldvari, A Heiligenhaus, J Anton, R Ramanan, C Edelsten, T Saurenmann, B Bodaghi, K Kotaniemi, S Nielsen, E Rabinovich, Multinational Interdisciplinary Working Group f...

Two colour flow cytometry techniques were used to assess the activation stages of peripheral and intraocular T lymphocytes in uveitis. Increased numbers of T lymphocytes bearing the interleukin-2 (IL-2) receptors were found in intraocular fluids or peripheral blood or both of 35/51 patients with uveitis. This increased expression of IL-2 receptors on lymphocytes correlated with increased expres...

Anterior uveitis or iridocyclitis is inflammation of the iris and ciliary body. This is the second most common ocular disease in cats, with FHV-1 related disease being number one. Many systemic diseases will first manifest as an anterior uveitis and the prognosis for not only the eyes but for the life of the animal may depend on identifying the systemic disease. Since few cats die as adults fro...

BACKGROUND Lyme arthritis is the most frequent late manifestation of Lyme borreliosis and has been associated with ocular inflammation. METHODS A group of 153 children and adolescents with arthritis, 84 of whom had Lyme arthritis and 69 other causes of arthritis, were followed prospectively for 22-73 (median 44) months in the course of a national study. RESULTS Three of 84 patients with Lym...

CONTEXT AND OBJECTIVE Acute anterior uveitis is a common extra-articular manifestation in spondyloarthritis patients. The aim of this study was to compare demographic, clinical, laboratory and treatment data among spondyloarthritis patients with and without acute anterior uveitis. DESIGN AND SETTING This was a cross-sectional analytical study at the Rheumatology Outpatient Clinic of the Evang...

OBJECTIVE To investigate the relationship between herpes zoster (HZ) and the subsequent risk of anterior uveitis during the year following an HZ diagnosis, using a nationwide population-based data set. METHODS This study used the Taiwan National Health Insurance Research Database. The study cohort consisted of 314,405 patients who received a diagnosis of HZ. The comparison cohort comprised 94...

Background Inflammatory ocular pathology (IOP) includes internal and external involvement. IOP may be severe conditions refractory to conventional immunosuppressants even biological therapy. Janus Kinase inhibitors (JAKINIB) had shown efficacy in cases of different immune-mediated inflammatory diseases (IMID). Objectives In patients with treated JAKINIB our aims were a ) assess the Spanish refe...