A subset of children develops persistent insulin autoantibodies (IAA; almost always as the only islet autoantibody) without evidence of progression to diabetes. The aim of the current study was the development and characterization of the performance of a nonradioactive fluid phase IAA assay in relation to standard IAA radioassay. We developed a nonradioactive IAA assay where bivalent IAA cross-...

The physiological activity of exogenous 4-Cl-IAA, as compared to IAA, was examined in maize coleoptile segments. It was found that in this model system 4-Cl-IAA is much more active in the stimulation of elongation than IAA. Simultaneous measurements of growth and external pH indicated that administration of either IAA or 4-Cl-IAA resulted in medium acidification. The kinetics of the pH changes,...

it,s nowadays proved that one can, from among many strains of rhyzobium species, find those which, in addition to high efficiency in n2 fixation, can positively affect such processes as plant growth (e.g. through production of plant growth hormones). such strains can be useful not only to their special host, but also to other plants as well as to strategic products as grains. soil biotechnology...

Indole acetic acid (IAA) is an important regulator of adventitious rooting via the activation of complex signaling cascades. In animals, carbon monoxide (CO), mainly generated by heme oxygenases (HOs), is a significant modulator of inflammatory reactions, affecting cell proliferation and the production of growth factors. In this report, we show that treatment with the auxin transport inhibitor ...

An in vitro study was conducted to determine the effects of the superior indole-3-acetic acid (IAA) producing Rhizobia and treatments of Ag and Ltryptophan (Trp) on wheat growth indices. Nine strains with different ability of IAA production (belonging to genus Rhizobium leguminosarum var. phaseoli and Rhizobium leguminosarum var. viciae, Sinorhizobium meliloti) and a non-inoculated control; two...

Three auxin analogs, 4-, 5-, and 6-azido-3-indoleacetic acid (4-N(3)-IAA, 5-N(3)-IAA, and 6-N(3)-IAA) have been synthesized for use as fluorescent photoaffinity labeling agents. The pK(a) values of these compounds (4-N(3)-IAA, 4.67; 5-N(3)-IAA, 4.65; 6-N(3)-IAA, 4.66; all +/- 0.04) are experimentally indistinguishable from the pK(a) of 3-indoleacetic acid (IAA, 4.69 +/- 0.04). The auxin activit...

AIMS Atrial Natriuretic Peptide (ANP)-containing amyloid is frequently found in the elderly heart. No data exist regarding ANP aggregation process and its link to pathologies. Our aims were: i) to experimentally prove the presumptive association of Congestive Heart Failure (CHF) and Isolated Atrial Amyloidosis (IAA); ii) to characterize ANP aggregation, thereby elucidating IAA implication in th...