نتایج جستجو برای: i3
تعداد نتایج: 2095 فیلتر نتایج به سال:
Lower esophageal sphincter (LES) tone depends on PGF(2alpha) and thromboxane A(2) acting on receptors linked to G(i3) and G(q) to activate phospholipases and produce second messengers resulting in muscle contraction. We therefore examined PGF(2alpha) signal transduction in circular smooth muscle cells isolated by enzymatic digestion from cat esophagus (Eso) and LES. In Eso, PGF(2alpha)-induced ...
Objective. Allantoin is the primary active compound in yams (Dioscorea spp.). Recently, allantoin has been demonstrated to activate imidazoline 3 (I3) receptors located in pancreatic tissues. Thus, the present study aimed to investigate the role of allantoin in the effect to improve damage induced in pancreatic β-cells by streptozotocin (STZ) via the I3 receptors. Research Design and Methods. T...
In view of the therapeutic importance of dopamine D(3) and D(2) receptors, there remains considerable interest in novel ligands. Herein, we show that the tetrahydroisoquinoline 1H-indole-2-carboxylic acid {4-[2-(cyano-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-cyclohexyl}-amide (SB269,652) behaves as an atypical, allosteric antagonist at D(3) and D(2) receptors. Accordingly, SB269,652 potently (lo...
به منظور بررسی اثر کمبودآب روی آب مصرفی وعملکرد دانه چهار رقم سورگوم دانه ای ‘ در سال 1369‘ آزمایشی در مزرعه تحقیقاتی دانشگاه اصفهان واقع در زغمار اصفهان انجام شد. این بررسی درقالب یک طرح آزمایشی کرتهای خرد شده با سه رژیم آبیاری i2,i1 و i3 که بترتیب آبیاری پس از 100‘ 150 و 200 میلیمتر تبخیر ازطشت تبخیر استاندارد کلاس a بود انجام پذیرفت . بدین ترتیب دور آبیاری درتیمارهای فوق از 100 میلیمتر تا 20...
A range of ligands displayed agonism at the long isoform of the human dopamine D(2) receptor, whether using receptor-G protein fusions or membranes of cells in which pertussis toxin-resistant mutants of individual Galpha(i)-family G proteins could be expressed in an inducible fashion. Varying degrees of efficacy were observed for individual ligands as monitored by their capacity to load [(35)S]...
Salts in the liquid phase at room temperature–ionic liquids– have recently received increased attention due to their unique properties.[1] These include high ionic conductivity, high thermal and chemical stability, broad electrochemical windows, non-volatility and non-flammability. These important properties make them versatile alternatives to conventional solvent-based systems, and their poten...
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