BACKGROUND The aim of the study was to investigate odor identification performance in patients one year after hospital admittance due to stroke. Predictors for olfactory dysfunction were investigated as well as self-reported olfactory function and pleasantness of olfactory items. METHODS A 1-year prospective study was performed. Stroke location, classification and comorbidities were registere...

Parkinson's disease (PD) is a neurodegenerative disease with both motor and non-motor manifestations. Hyposmia is one of the early non-motor symptoms, which can precede motor symptoms by several years. The relationship between hyposmia and PD remains elusive. Olfactory bulb (OB) pathology shows an increased number of olfactory dopaminergic cells, protein aggregates and dysfunction of neurotrans...

BACKGROUND AND PURPOSE Excessive daytime sleepiness and sudden sleep attacks are the main features of narcolepsy, but rapid-eye-movement sleep behavior disorder (RBD), hyposmia, and depression can also occur. The latter symptoms are nonmotor features in idiopathic Parkinson's disease (IPD). In the present study, IPD-proven diagnostic tools were tested to determine whether they are also applicab...

INTRODUCTION The large increase in the number of transnasal endoscopic skull base surgeries is a consequence of greater knowledge of the anatomic region, the development of specific materials and instruments, and especially the use of the nasoseptal flap as a barrier between the sinus tract (contaminated cavity) and the subarachnoid space (sterile area), reducing the high risk of contamination....

INTRODUCTION Hypogonadotropic hypogonadism (HH) is a heterogeneous disease caused by mutations in several genes. Based on the presence of hyposmia/anosmia it is distinguished into Kallmann syndrome (KS) and isolated HH. The prevalence of other developmental anomalies is not well established. METHODS We studied 36 patients with HH (31 males, 5 females, mean age 41.5), 9 with familial and 27 wi...

Synucleinopathies (including α-synucleinopathies), which include Parkinson's disease (PD), manifest themsevles early on (stage 1) in the olfactory system; preferentially in the anterior olfactory nucleus (AON). In particular, the non-motor, early manifestations of PD include hyposmia, which is the partial loss of the sense of smell. The neural basis of hyposmia in PD, however, is poorly underst...

Idiopathic intracranial hypertension (IIH), also known as pseudotumor cerebri, preferentially affects obese women of childbearing age. Although the precise etiology of IIH remains to be fully established, elevated intracranial pressure (ICP) clearly constitutes a hallmark pathologic feature of the condition. Affected individuals regularly suffer from signs and symptoms of increased ICP such as ...

improvement in nasal symptoms (congestion and hydrorrhea, and, to a lesser extent, hyposmia); 2 months later she had also achieved better asthma control (no further need for rescue bronchodilator use and no asthma symptoms, leading to the withdrawal of inhaled corticosteroids and long-acting ß 2 agonists, and a signifi cant improvement of FEV 1 up to 90% of predicted). After 16 weeks of treatme...