Previous studies on statin have revealed that increasing age, renal insufficiency, and concomitant medications were associated with rhabdomyolysis. However, there is a lack of analysis on the magnitude of such association in the Asia-Pacific region. The objectives of this study were to identify risk factors of statin-associated rhabdomyolysis in Thai patients and to evaluate the magnitude of as...

OBJECTIVE Rhabdomyolysis is a rare and potentially serious adverse drug reaction (ADR) to antipsychotic medicines. The aim of this study was to investigate the clinical circumstances surrounding the diagnosis of rhabdomyolysis in children and adolescents treated with antipsychotic medicines. We also critically reviewed individual case safety reports (ICSRs) of suspected ADRs to evaluate how cli...

Hyponatremia is one of the most frequent laboratory findings in hospitalized children. We present an unusual case of recurrent hyponatremia in a 16-year-old female secondary to acute intermittent porphyria (AIP), a rare inborn error of metabolism. The proposed mechanism of the hyponatremia and recommended treatment are discussed. Although rare, AIP should be considered in children with recurren...

Influenza virus is the most frequently reported viral cause of rhabdomyolysis. A 7-year-old child is presented with rhabdomyolysis associated with parainfluenza type 2 virus. Nine cases of rhabdomyolysis associated with parainfluenza virus have been reported. Complications may include electrolyte disturbances, acute renal failure, and compartment syndrome.

Rhabdomyolysis is a clinical picture which is rarely seen in children. In this case report here it is presented a patient who has biochemical and clinical signs of rhabdomyolysis and admitted to our clinic with hypernatremia. The authors think that it is necessary to be alert for rhabdomyolysis in severe hypernatremia cases.

OBJECTIVES To evaluate whether the serum sodium concentration is associated with the progression and long-term prognosis of Chinese HIV/AIDS patients. METHODS Three hundred and eighty seven hospitalized patients were recruited into this retrospective cohort study. The strata of serum sodium concentration were moderate/severe hyponatremia, mild hyponatremia and normonatremia. Disease progressi...

H yponatremia represents a serious health hazard. 1 Hospitalized patients, nursing home residents, women, and children exhibit high frequency and/or severity of hyponatremia. Hyponatremia developing during the course of other morbid conditions increases their severity. Estimates of direct costs for treating hyponatremia in the United States ranged between $1.61 and $3.6 billion. Clinical manife...

BACKGROUND Some case reports showed unexplained hyponatremia in patients with cardiac tamponade. Reversible hyponatremia was observed in these patients who received pericardial drainage. The occurrence rate of hyponatremia in patients of cardiac tamponade is not clearly known. The objective of this study was to identify the relationship between hyponatremia, cardiac tamponade and their underlyi...

BACKGROUND Due to the alarming increase in the incidence of thyroid cancer worldwide, more patients are receiving postoperative radioactive iodine (RAI) therapy and these patients are given a low-iodine diet along with levothyroxine withdrawal to induce a hypothyroid state to maximize the uptake of RAI by thyroid tissues. Recently, the reported cases of patients suffering from life-threatening ...

PURPOSE OF REVIEW Drug-induced rhabdomyolysis is a common syndrome that is complex and potentially life threatening. This article reviews the pathophysiology, clinical presentations, and common compounds that cause drug-induced rhabdomyolysis. RECENT FINDINGS The list of drugs and inciting agents that cause rhabdomyolysis is quite extensive. Rhabdomyolysis is defined as skeletal muscle injury...