BACKGROUND Hip fractures in the older person lead to an increased risk of mortality, poorer quality of life and increased morbidity. Benzodiazepine (BNZ) use is associated with increased hip fracture rate, consequently Z-drugs are fast becoming the physician's hypnotic prescription of choice yet data on their use is limited. We compared the risk of hip fracture associated with Z-drugs and BNZ m...

BACKGROUND Recent molecular strategies demonstrated that the N-methyl-d-aspartate (NMDA) receptor is a major target site of anesthetic agents. In a previous article, the authors showed that knocking out the NMDA receptor epsilon1 subunit gene markedly reduced the hypnotic effect of ketamine in mice. In the current study, the authors examined the in vivo contribution of the NMDA receptor epsilon...

Hypnotic suggestibility has been described as a powerful predictor of outcomes associated with hypnotic interventions. However, there have been no systematic approaches to quantifying this effect across the literature. This meta-analysis evaluates the magnitude of the effect of hypnotic suggestibility on hypnotic outcomes in clinical settings. PsycINFO and PubMed were searched from their incept...

This study examined whether trait empathy is related to hypnotic ability and absorption. Sixty-four graduate students and mental health professionals completed the Harvard Group Scale of Hypnotic Susceptibility, Form A; the Davis Interpersonal Reactivity Index; and the Tellegen Absorption Scale as measures of hypnotic ability, empathy, and absorption. Correlation analysis determined that statis...

Forming implementation intentions has been consistently shown to be a powerful self-regulatory strategy. As the self-regulation of thoughts is important for the experience of involuntariness in the hypnotic context, investigating the effectiveness of implementation intentions on the suppression of thoughts was the focus of the present study. Participants were randomly assigned to one of four co...

In this article, hypnotic responsiveness is conceptualized as the byproduct of hypnotic ability, which is largely unalterable, plus hypnotic participation, which is highly subject to manipulation in the therapeutic context. This framework constitutes the basis of a model for the conversational assessment of hypnotic ability and hypnotic participation, as well as the subsequent tailoring of ther...

In critically ill COVID-19 patients, proper management of sedation is an important issue. Therefore, for this purpose, several strategies and protocols have been proposed. paper, we illustrate approach focused on lung damage, both the pharmacokinetic pharmacodynamic profiles drugs used. line with this, during high flow nasal (HFN), continuous positive airway pressure, or non-invasive ventilatio...

In this paper some models are applied to analyze insomnia data. Insomnia is a sleep disorder in which the patient does not get enough or satisfactory sleep and investigating the use of hypnotic drug for its cure is so important. For studying the effect of drugs on insomnia, it is useful to observe the response of interest (cured or not cured) for each subject repeatedly at several times. So, a ...

Background: Discrepancies between objectively and subjectively measured sleep variables make diagnosing insomnia in the elderly difficult. Also relevant to diagnosing insomnia in the elderly are expectations about sleep, gender and use of sedative-hypnotic medication. The present study focuses on how these variables relate to insomnia and sleep satisfaction. Method: A questionnaire focusing on ...