The relationship between thirst perception and plasma osmolality was studied during hypertonic and physiological saline infusion in ten healthy volunteers. Thirst perception was quantified using a linear visual analogue scale which volunteers marked at intervals during the infusion periods. Infusion of hypertonic saline caused a steady rise in plasma osmolality together with a progressive linea...

The success of home telemedicine depends on end-user adoption, which has been slow despite rapid advances in technological development. This study focuses on an examination of significant factors that may predict the successful adoption of home telemedicine services (HTS) among older adults. Based on previous studies in the fields of remote patient monitoring, assisted living technologies, and ...

First, outcome variable of “duration of comatose state” included all patients irrespective of their survival status. Failure to censor this time-to-event ‘duration of coma’ variable by mortality in this study is a major methodological flaw in evaluating treatment efficacy. Indeed, more aptly definable endpoint would be the “duration of resolution of abnormal mental status (or length of time to ...

Setting: Mulanje District, Malawi. Objective: To examine the effectiveness of door-to-door (DtD) testing in reaching young people and men in a remote, rural area with a high prevalence of human immunodeficiency virus (HIV) infection. Design: This was a retrospective analysis of data collected for a pilot DtD program. HIV testing services (HTS) visited targeted villages for 1-2 weeks. All curren...

An extensive interlaboratory comparison was conducted on high temperature superconductor (HTS) critical-current measurements. This study was part of an international cooperative effort through the Versailles Project on Advanced Materials and Standards (VAMAS). The study involved six U.S. laboratories that are recognized leaders in the field of HTS. This paper includes the complete results from ...

Note: Prof. Dr Warren Carter is a member of the editorial board of HTS Teologiese Studies/Theological Studies; this article is dedicated to Prof. Dr Andries G. van Aarde with appreciation for his generous spirit, energetic leadership and insightful and creative scholarship. Prof. Dr Warren Carter is also participating as research associate of Prof. Dr Andries G. van Aarde, Honorary Professor in...

Introduction The pathogenesis of AKI is characterized by a deterioration in tissue perfusion and oxygenation in combination with inflammation resulting in renal microcirculatory dysfunction and kidney failure. Hypertonic saline (HS) solution increases serum osmolarity which results in an redistribution of fluid from the interstitial and intracellular spaces to the intravascular space potentiall...

The present review discusses the hemodynamic effects of hypertonic saline in experimental shock and in patients with sepsis. We comment on the mechanisms of action of hypertonic saline, calling upon data in hemorrhagic and septic shock. Specific actions of hypertonic saline in severe sepsis and septic shock are highlighted. Data are available that support potential benefits of hypertonic saline...