Endogenous secretory receptor (esRAGE) for advanced glycation end-product (AGE) acts as decoy for AGEs. The AGE-to-esRAGE ratio was hypothesized to be implicated in diabetic vasculopathy. We investigated an association of esRAGE and methylglyoxal-adducts serum level, as well as AGE-to-esRAGE ratio in subpopulation of diabetic patients with or without concomitant hyperlipidemia and macrovascular...

Recently, epidemiological studies on the etiology of peripheral neuropathies have revealed that hyperlipidemia is a novel risk factor. Plasma lipid levels were confirmed to be associated with the incidence of many peripheral neuropathies including axonal distal polyneuropathy, vision and hearing loss, motor nerve system lesions and sympathetic nerve system dysfunction. Moreover, different lipid...

A study of nephrotic syndrome in pediatric patients admitted in Gandhi and Niloufer hospital, Hyderabad, Andhra Pradesh, is presented here with special emphasis on serum protein levels and lipid profile. Out of the total cases, more than half were males with onset before 5 years of age. A definite significant inverse correlation existed between T. protein & triglycerides; albumin & triglyceride...

A case is presented of a 15-year-old boy with a past medical history of hyperlipidemia and hypertension. He attended the emergency department with a 3-day history of vomiting, acute abdominal pain, and altered mental status. Laboratory data on admission revealed metabolic acidosis (pH: 7.12, BE: -20.8 mmol/L), high blood glucose level (32.1 mmol/L) and significant hyperlipidemia (cholesterol: 1...

Pulp stones signify the calcification of discrete origin seen in pulp tissues and are either embedded or attached to dentin. can be a pathological physiological entity. The pathogenesis stone formation is idiopathic. However, various theories have been proposed. frequency range 8% 90%. They more identified on histopathologic examination than radiographic assessment. present study aimed assess c...

Hyperlipidemia is a condition which comprises several acquired and genetic disorders that cause elevated lipid levels in the body. The lipids may further lead to various health complications such as arteriosclerosis, cardiovascular disease, cerebrovascular peripheral vascular diseases. A 41-year-old male, non-alcoholic, non-smoking, vegetarian, self-employed patient reported with chronic abnorm...

The development of the remnant like particle (RLP) method for conveniently measuring serum remnant lipoprotein levels in 1993 promoted much research on atherogenic significance and metabolism of remnant lipoproteins. This research brought about many results as the following. A novel apolipoprotein B48 receptor incorporating remnant lipoproteins into macrophages in arterial wall was discovered a...