BACKGROUND Conventional meta-analysis has estimated the sensitivity and specificity of hysterosalpingography (HSG) to be 65% and 83%. The impact of patient characteristics on the accuracy of HSG is unknown. The aim of this study was to assess by individual patient data meta-analysis whether the accuracy of HSG is associated with different patient characteristics. METHODS We approached authors...

Health risk of human exposure to microcystin-leucine arginine (MC-LR) has aroused more and more attention over the past few decades. In the present study, MC-LR was orally administered to female mice at 0, 1, 10 and 40 μg/L for three and six months. We found that chronic exposure to MC-LR at environmental levels could stimulate follicle atresia and lead to decreased developmental follicles, acc...

BACKGROUND Understanding the aetiology of subfertility and female reproductive tract disorders at a molecular level may improve success rates in fertility treatment. Such understanding may be gained by the application of metabonomics technologies to tissues or biofluids. Metabonomics is concerned with the quantification of molecules in the metabolome and uses nuclear magnetic resonance (NMR) sp...

BACKGROUND Subfertility in general practice is a common problem. However, most treatment is initiated in hospital. There may be a role for general practitioners in the treatment of some infertile patients. AIM The aim of this study was to investigate the prevalence and management of infertility in women in general practice and to identify a specific cohort of patients potentially suitable for...

Obesity is clearly becoming a worldwide pandemic and is now considered a disease that recent data have shown it affects more than one third of the adult population in the United States [1]. Obesity affects female reproduction [2-6] since compelling data showed that obese women are more predisposed to subfertility [7], have increased risk of miscarriages [8] and are more prone to having pregnanc...

Reduced fertility associated with fluid accumulation has been recognized for many years in broodmares. This subfertility is caused by an unsuitable environment for the developing conceptus within the uterus, and in some cases, the ensuing endometritis persists and causes early regression of the corpus luteum (CL). Persistent mating-induced endometritis has come to be recognized as a major reaso...

being either underweight or overweight can affect a woman's fertility. irregular menstrual cycles, reduced spontaneous and assisted fertility and an increased risk of miscarriage are risks associated with obesity that are often overlooked. excessive weight and central distribution of body fat are both related to an increased risk of normogonadotrophic anovulation. weight loss can re-establish o...

background: with the technical development, ultrasound tends to overpass its limits and to become the main investigation tool even for situations when it was traditionally considered second best. it is more convenient both for patient and doctor, less expensive and has real diagnostic value. objective: the present paper, and its graphic back-up, are intended as a visual testimony of the fact th...

According to a number of high quality studies intrauterine insemination (IUI) with homologous semen should be the first choice treatment in case of unexplained and moderate male factor subfertility. IVF and ICSI are clearly over-used in this selected group of infertile couples. The limited value of IUI in infertility treatment as mentioned in the 2013 NICE guidelines was surely a premature stat...

objective: to compared serum crp levels and biochemical relation in pcos patients with normal iranian women. materials and methods: this case-control study was performed on 52 individuals with pcos (rotterdam 2003 criteria). the cases were compared to 104 healthy non-pcos, 20 to 35-year-old female subjects with no history of diabetes or renal diseases. blood samples were taken on the 2(nd) to t...