نتایج جستجو برای: hyperemia

تعداد نتایج: 4340  

2014
Hou-Jen Chen Graham A Wright

Background Evidence suggests that microvascular function may be compromised in Peripheral Arterial Disease (PAD) due to associated endothelial dysfunction. While revascularization is recommended for PAD patients with macrovascular occlusions, a solution for endothelial dysfunction remains unavailable. For a possible endothelium-targeted therapy to be applied, the burden of endothelial dysfuncti...

Journal: :JACC. Cardiovascular imaging 2015
Nils P Johnson K Lance Gould

OBJECTIVES The goal of this study was to compare regadenoson and dipyridamole hyperemia for quantitative myocardial perfusion imaging. BACKGROUND Regadenoson is commonly used for stress perfusion imaging. However, no study in nuclear cardiology has employed a paired design to compare quantitative hyperemic flow from regadenoson to more traditional agents such as dipyridamole. Additionally, th...

Journal: :Eye & contact lens 2006
Colleen Riley Graeme Young Robin Chalmers

PURPOSE Many soft contact lens wearers have symptoms or signs that compromise successful lens wear. This study estimated the prevalence of problems in current wearers of soft contact lenses and tested the effect of refitting patients with senofilcon A silicone hydrogel lenses (ACUVUE Oasys). METHODS Prevalence was estimated from 1,092 current lens wearers for frequent or constant discomfort o...

Journal: :American journal of physiology. Heart and circulatory physiology 2004
Ji Song Patrick S Cottler Alexander L Klibanov Sanjiv Kaul Richard J Price

We showed previously that microbubble destruction with pulsed 1-MHz ultrasound creates a bioeffect that stimulates arteriogenesis and a chronic increase in hyperemia blood flow in normal rat muscle. Here we tested whether ultrasonic microbubble destruction can be used to create a microvascular remodeling response that restores hyperemia blood flow to rat skeletal muscle affected by arterial occ...

Journal: :Circulation. Cardiovascular interventions 2013
Koichiro Fujisue Seigo Sugiyama Takamichi Ono Yasushi Matsuzawa Eiichi Akiyama Koichi Sugamura Junichi Matsubara Hirofumi Kurokawa Koichi Kaikita Satomi Iwashita Hitoshi Sumida Seiji Hokimoto Kentaro Oniki Kazuko Nakagawa Kunihiko Matsui Hisao Ogawa

BACKGROUND Dual antiplatelet therapy with aspirin and clopidogrel is widely used in patients with coronary stents. High residual platelet reactivity (high RPR) after dual antiplatelet therapy is associated with increased cardiovascular events. Endothelial function could affect platelet reactivity in vivo. We hypothesized that endothelial dysfunction could be associated with high RPR after dual ...

Journal: :Hypertension 1999
Y Higashi S Sasaki N Sasaki K Nakagawa T Ueda A Yoshimizu S Kurisu H Matsuura G Kajiyama T Oshima

The effects of long-term aerobic exercise on endothelial function in patients with essential hypertension remain unclear. To determine whether endothelial function relating to forearm hemodynamics in these patients differs from normotensive subjects and whether endothelial function can be modified by continued physical exercise, we randomized patients with essential hypertension into a group th...

Journal: :American journal of physiology. Heart and circulatory physiology 2007
Marvin S Medow Indu Taneja Julian M Stewart

We tested the hypothesis that cyclooxygenases (COXs) or COX products inhibit nitric oxide (NO) synthesis and thereby mask potential effects of NO on reactive hyperemia in the cutaneous circulation. We performed laser-Doppler flowmetry (LDF) with intradermal microdialysis in 12 healthy volunteers aged 19-25 yr. LDF was expressed as the percent cutaneous vascular conduction (%CVC) or as the maxim...

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