Localized neonatal subcutaneous fat necrosis has been well recognized since the description of Fabyan (1907). Since then many case reports have been published: thus Masi and Brancolini (1956) collected 179 reported cases. Calcium deposition in affected tissues was described by Harrison and McNee (1926) and a raised serum calcium was reported in one of their cases. The association of this condit...

Although the kidneys are infrequently involved in sarcoidosis, physicians involved in taking care of sarcoidosis patients need to be aware of this possibility in order to diagnose and treat this dangerous disorder before it causes serious damage. Sarcoidosis may either involve the kidneys directly or cause renal failure secondary to hypercalcaemia, hypercalciuria and nephrocalcinosis. Hypercalc...

INTRODUCTION Most cases of hypercalcaemia are secondary to malignancy or primary hyperparathyroidism. Here we report a case of hypercalcaemia that we have attributed to milk-alkali syndrome. CASE PRESENTATION A 51-year-old Caucasian woman with a past history of thyroidectomy and parathyroidectomy secondary to thyroid cancer developed an altered mental state and had an extremely high calcium c...

The hypercalcaemia in association with trisomy 21 (Down's syndrome) is often not recognised and therefore underdiagnosed. Patients present the tetrad of hypercalcaemia, Down’s syndrome, renal impairment, nephrocalcinosis. 1-3 
 A 30-month old child syndrome had a long history nonspecific symptoms, constipation feeding difficulties. He was on excessive bottle feeds, taking 14 bottles daily,...

Background: Metabolic syndrome (Mets) is a risk factor for cardiovascular, chronic lung, liver and kidney diseases. Hypercalcaemia, hypomagnesaemia elevated C-reactive protein (CRP) produce various complications such as cardiac arrythmia, renal stones, atherosclerosis, Diabetes Mellitus, Obesity etc. Some researchers suggested that hypercalcaemia, CRP occur in patients. Objectives: To measure s...

OBJECTIVE Familial hypocalciuric hypercalcaemia (FHH) is clinically characterized by mild to moderate parathyroid hormone (PTH)-dependent hypercalcaemia, autosomal dominant pattern of inheritance, and normal to frankly reduced urinary calcium excretion in spite of a high serum calcium (clearance (Ca)/clearance (Cr)<0.01). FHH has a benign course and should be differentiated from primary hyperpa...

A study is reported of the estimation of plasma chloride concentration and acid-base status in the differentiation of primary hyperparathyroidism from all other causes of hypercalcaemia. In the two groups of patients studied, all of whom had hypercalcaemia, there was complete separation between the two groups on the basis of plasma chloride concentration and acid-base status. In 16 patients wit...

The factors causing congenital heart disease, apart from the well known effects of rubella in the mother during the first three months of pregnancy, are in general obscure. The association of congenital heart disease with Multiple non-cardiac abnormalities may form the basis for an investigation }nto other aetiological factors. The combination of cardiac defects with mfantile hypercalcaemia is ...