Thermolysis of a diazirine end group Br-functional PCL leads to carbene generation and subsequent hyperbranched polymers. Grafting hydrophilic PEG yields amphiphilic polymers which self-assemble into spherical core–shell nanoparticles.

Preferred-handed twist was induced by CPL to covalent organic frameworks (COF’s) and hyperbranched polymers where the internal rotation rate in COF’s estimated solid-state NMR found affect chirality induction efficiency.

Successful systemic gene therapy has been hindered by vector-related limitations, including toxicity and inefficient gene delivery to tumor cells after i.v. administration. To circumvent these problems, we developed a novel formulation between the polycation polyethyleneimine and DNA that mediates high-level tumor cell transduction in vitro and efficient i.v. gene delivery in that greater repor...

A novel hyperbranched polymer gelator has been synthesized, which can self-assemble into the thermoreversible physical gel in DMF, DMAC, pyridine, DMSO or NMP with the driving force of hydrogen bonds among amide and amine groups of the highly branched macromolecules.

Lightly branched, hyperbranched and cross-linked polymers with clickable sites were synthesized via a modified version of self-condensing photoinitiated copolymerization of methyl acrylate (MA) with propargyl acrylate (PA). The method is based on the use of a PA monomer containing two polymerizable groups, namely acrylate and propargyl groups with different reactivities in photoinitiated free r...

A new polymer acid catalyst, sulfonated hyperbranched poly(arylene oxindole), 5-OH-SHPAO, was prepared for selective cellulose hydrolysis. Its superior catalysis, showing high glucose selectivity at almost full cellulose conversion, is attributed to the presence of an hydroxyl group next to the sulfonic acid, therefore mimicking the separate acid-base pair in the cellulase active site.

Here we demonstrate a simple and straightforward approach to prepare POSS-embedded hyperbranched (HB-POSS) polymers with customized molecular weights and sizes just by controlling the polymerization time. The polymers can be further used for building amphiphilic polymers, presenting morphological transition from micelle to vesicle in aqueous solution.

Echis carinatus (saw-scaled viper) produces potent hemorrhagic venom that causes the development of apoptotic and necrotic tissues. In this study, we used polyethyleneimine (PEI) to enhance cellular adherence, and to determine whether the substrate attachment influenced the survival of cells treated with crude E. carinatus venom. Human embryonic kidney (HEK) 293T cells were grown for 18hr in ti...