Lorazepam 2 and 4 mg alone and in combination with atropine 0.4 mg and hyoscine 0.4 mg were studied as i.v. surgical premedicants in 150 patients. Relief of anxiety, sedation, patient acceptance, lack of recall and side-effects were evaluated. Hyoscine was found to improve the relief of anxiety and sedation associated with lorazepam, but did not significantly increase lack of recall or patient ...

A standard operative procedure and anaesthetic technique were employed to compare the effects of 0.6 mg atropine and 0.4 mg hyoscine, given as part or all of premedication, on the course of thiopentone anaesthesia. The incidence and severity of muscle movement following induction was increased by the use of hyoscine, but not to the same extent as previously found with methohexitone. This effect...

BACKGROUND Unripe cervix prevents entering the endometrial cavity during intrauterine procedures. Mechanical dilatation of cervical canal might cause undesirable complications. OBJECTIVE To investigate the substitute of mechanical intervention with chemical treatment by administering hyoscine to patients. MATERIALS AND METHODS Sixty non-pregnant women, 20-70 years of age, with a closed cerv...

An investigation was made of the effects of I mg. hyoscine hydrobromide and of 50 mg. meclozine hydrochloride on the performance of tasks of vigilance and short-term memory. In further trials the effects of these drugs were measured after ingestion of 32 g. ethyl alcohol. Efficiency was impaired by hyoscine taken alone, but meclozine alone had no significant effect. The effect of hyoscine was s...

Intestinal obstruction may be duo to various mechanical or functional reasons. Worms, especially Ascaris worms are one of the mechanical reasons of intestinal obstruction. Obstruction due to Taenia saginata is a rare phenomenon. Here we report a case of intestinal obstruction due to Taenia saginata infection in a 30 year-old male patient undergoing laparatomy with the diagnosis of intestinal ob...

Forty-two patients, undergoing major gynaecological surgery, were randomly allocated to have a patch applied to the skin behind one ear, containing either hyoscine or placebo. They were followed up at 24-hour intervals for 3 days postoperatively and divided into matched pairs for statistical analysis. There was a significant (p less than 0.01) reduction in nausea and vomiting in the first 24 ho...

purpose: oculocardiac reflex (ocr) is a frequent event during strabismus surgery. the aim of this study is to compare the preventive effect of intravenous lidocaine and hyoscine on ocr.methods: this prospective, randomized clinical trial was performed on 75 patients (5-63 years old) underwent strabismus surgery. patients divided randomly into three groups. intravenous hyoscine (0.2 mg/kg), lido...

BACKGROUND Nonanesthetic colonoscopy is popular in clinical practice in China. However, intestinal spasms often result in a prolonged examination time, increased operating difficulties, decreased polyp detection rate, and failure to complete the procedure clinically. Therefore, exploring alternative approaches that can reduce the pain in patients during colonoscopy is of utmost importance, and ...

in order to determine prevalence of echinoccocus and other intestinal helminths infection one hundred stray dogs were examined in mashhad area, khorasan province of iran. helminths were collected from intestinal contents obtained at the time necropsy. ninety one percent of the dogs were infected by different helminths. the prevalence of echinococcus granulosus was (22%). eighteen (81%) of infec...

In a double-blind, randomized study, we have compared the efficacy of transdermal hyoscine in the prevention of nausea and vomiting with placebo in 60 young, ASA I-II patients after middle ear surgery during general anaesthesia. In the placebo group, 27% and 43% of patients suffered from nausea and vomiting, respectively, during the first 24 h after anaesthesia. The corresponding values for bot...