نتایج جستجو برای: hyola 401
تعداد نتایج: 4825 فیلتر نتایج به سال:
labile group of amino acids to a diphtheria toxin (DT) payload that has been truncated at its receptor binding region. Since IL-3, the natural ligand for IL-3R, binds with very high specificity and avidity, SL-401 is able to transport DT efficiently and preferentially to cells that overexpress IL-3R, leading to internalization followed by receptor-mediated endocytosis and localization of SL-401...
Our laboratory previously developed a highly-invasive, triple-negative breast cancer (TNBC) variant using serial orthotopic implantation of the human MDA-MB-231 cell line in nude mice. The isolated variant was highly-invasive in the mammary gland and lymphatic channels and metastasized to lymph nodes in 10 of 12 mice compared to 2 of 12 of the parental cell line. In the present study, the tumor...
OBJECTIVE International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) diagnosis codes are increasingly used to identify healthcare-associated infections, often with insufficient evidence demonstrating validity of the codes used. Absent medical record verification, we sought to confirm a claims algorithm to identify surgical site infections (SSIs) by examining the ...
We have previously developed a genetically-engineered GFP-expressing telomerase-dependent adenovirus, OBP-401, which can selectively illuminate cancer cells. In the present report, we demonstrate that targeting a triple-negative high-invasive human breast cancer, orthotopically-growing in nude mice, with OBP-401 enables curative fluorescence-guided surgery (FGS). OBP-401 enabled complete resect...
Two issues may have a tremendous impact on the adequacy of retirement income for American workers. The first is the growth of 401(k) pension plans, which allow participants to contribute, before taxes, a portion of their salary to a qualified retirement account.1 By 1998, the most recent year that published information is available, 401(k) plans accounted for about 41 percent of all pension pla...
This is especially true in smaller companies and those of fairly recent vintage because 401(k)s are likely to be the only retirement program offered in these organizations. But, even in large and old-line businesses in which traditional defined benefit (DB) pension plans remain common, it’s important for employees to take responsibility for their retirement planning and save for retirement in o...
A sensitive and selective method was developed for the separation and characterization of related substances (RSs) in EVT-401 by hyphenated LC-MS techniques. Complete separation of the RSs was achieved with an Inertsil ODS-SP column (250 mm×4.6 mm, 5 µm) by linear gradient elution using a mobile phase consisting of 0.2% formic acid solution, methanol and acetonitrile. EVT-401 was found to be su...
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