This study aimed to introduce a new method based on Hollow Fiber in order to determination of acetic anhydride (AA) in the air. Hydroxylamine hydrochloride and sodium hydroxide (1:1), were used as extraction solvent. This method was studied in the laboratory under various conditions. In order to make different concentrations of AA in the air, a standard glass chamber was used. The optimization ...

Alpha-phenyl-N-t-butyl nitrone (PBN), a spin trap, scavenges hydroxyl radicals, protects tissues from oxidative injury, and delays senescence of both normal human lung fibroblasts (IMR90) and senescence-accelerated mice. N-t-butyl hydroxylamine and benzaldehyde are the breakdown products of PBN. N-t-Butyl hydroxylamine delays senescence of IMR90 cells at concentrations as low as 10 microM compa...

The formation and elimination of sulphamethoxazole hydroxylamine in relation to the pharmacokinetics of the parent compound and its N4-acetyl metabolite were investigated in six healthy subjects after a single oral dose of 800 mg sulphamethoxazole. The apparent half-lives of sulphamethoxazole and its metabolites were approximately 10 h, indicative of formation rate-limited metabolism. The mean ...

Nitrite reductase has been separated from cell-free extracts of Nitrosomonas and partially purified from hydroxylamine oxidase by polyacrylamide-gel electrophoresis. In its oxidized state the enzyme, which did not contain haem, had an extinction maximum at 590nm, which was abolished on reduction. Sodium diethyldithiocarbamate was a potent inhibitor of nitrite reductase. Enzyme activity was stim...

a rapid, specific and accurate proton quantitative nuclear magnetic resonance spectroscopic (1h qnmr) and also a reversed phase derivatization hplc method have been developed to quantify a toxic, uv-visible inactive and non-volatile impurity n,n-dimethylamine hydrochloride (dma∙hcl) in metformin hydrochloride (mf∙hcl), an active pharmaceutical ingradient. the method is based on proton quantitat...

the synthesis of N-aminopiperidine (NAPP) using hydroxylamine-O-sulfonic acid (HOSA) is based on system nonlinear rate equations. The new approach to homotopy perturbation method applied solve A simple analytical expression for concentrations hydroxylamine-O-sulfonique (HOSA), piperidine (PP), (NAPP), sodium hydroxide (NaOH) and diazene (N2H2) along with NAPP yield obtained compared numerical r...

Hydroxylamine (NH(2)OH) is an unstable compound at room temperature, and it has been involved in two tragic industrial incidents. Although experimental studies have been carried out to study the thermal stability of hydroxylamine, the detailed decomposition mechanism is still in debate. In this work, several density functional and ab initio methods were used in conjunction with several basis se...