The enantioselective silylation of racemic alcohols, where one enantiomer reacts faster than the other, is an alternative approach to established enzymatic and non-enzymatic acylation techniques. The existing art is either limited to structurally biased alcohols or requires elaborate catalysts. Simple substrates, such as benzylic and allylic alcohols, with no coordinating functionality in the p...

The title monohydrate, C9H10N2O3·H2O, contains an aziridine ring including two contiguous stereocenters, both of which exhibit an R configuration. The methyl-hydroxy and nitro-phenyl groups are cis-disposed about the aziridine ring. The mean plane of the benzene ring is tilted to the aziridine ring by 66.65 (8)°. The nitro group is nearly coplanar with the benzene ring [dihedral angle = 2.5 (2)...

The copper-catalyzed ketenimine formation reaction of 1-(o-acetamidophenyl)propargyl alcohols with various sulfonyl azides is found to undergo a concomitant intramolecular nucleophile attack to generate 1,2-dihydro-2-iminoquinolines after aromatization (via elimination of acetyl and hydroxy groups) and tautomerization. The reaction produces 4-substituted and 3,4-unsubstituted title compounds in...

The central Ni atom of the title compound, [Ni(C(29)H(29)N(3)O(4))], is coordinated by three N atoms [Ni-N = 1.955 (2), 1.844 (2) and 1.872 (2) Å] and by one O atom [Ni-O = 1.862 (2) Å] in a pseudo-square-planar geometry. The conformation of the hydroxy-butanoate side chain is controlled by a strong intra-molecular hydrogen bond (H⋯O = 1.84 Å).

The asymmetric unit of the title compound, C(5)H(9)N(2) (+)·C(8)H(5)O(4) (-), consists of one protonated 2-ethyl-imidazolium cation and two half terephthalate anions. The anions and cations are linked through N-H⋯O hydrogen bonds while the anions are associated via O-H⋯O inter-actions, resulting in a layered structure. The ethyl group of the cation is disordered over twosites of occupancies 0.8...

Alk-2-enylstannanes with 4-, 5- and 6-alkoxy- or -hydroxy-substituents are transmetallated stereoselectively with tin(iv) halides to generate allyltin trihalides which react with aldehydes to give (Z)-alk-3-enols with useful levels of 1,5-, 1,6- and 1,7-stereocontrol. Alk-2-enylstannanes with a stereogenic centre bearing a hydroxy or alkoxy group at the 4-, 5- or 6-position, react with overall ...

A series of methylated β-cyclodextrins (CDs) regioselectively leaving one or two hydroxy groups were prepared, and fluorescence spectroscopic measurements showed that they have unique binding characteristics against 2-p-toluidinylnaphthalene-6-sulfonate as a guest molecule in aqueous solution.

Spontaneous and near-infrared/infrared (NIR/IR)-induced interconversions between two amino-hydroxy conformers of monomeric cytosine have been investigated for the compound isolated in a low-temperature argon matrix. Combined use of a laser source (which provides narrowband NIR radiation) and a broadband NIR/IR source of excitation light allowed a detailed investigation of mutual conversions of ...

The title compound, C(18)H(13)ClO(3), has an intra-molecular O-H⋯O=C hydrogen bond between the carbonyl group and the hydr-oxy substituent on the naphthalene ring system. The angle between the C=O bond plane and the naphthalene ring system is relatively small [20.96 (8)°]. The angle between the benzene ring and the carbonyl group is rather large [35.65 (9)°] compared to that in an analogous com...