نتایج جستجو برای: hydroxychloroquine

تعداد نتایج: 3155  

2014
David J Browning Chong Lee David Rotberg

PURPOSE To determine how algorithms for ideal body weight (IBW) affect hydroxychloroquine dosing in women. METHODS This was a retrospective study of 520 patients screened for hydroxychloroquine retinopathy. Charts were reviewed for sex, height, weight, and daily dose. The outcome measures were ranges of IBW across algorithms; rates of potentially toxic dosing; height thresholds below which 40...

2013
Nelly Mezzaroba Sonia Zorzet Erika Secco Stefania Biffi Claudio Tripodo Marco Calvaruso Ramiro Mendoza-Maldonado Sara Capolla Marilena Granzotto Ruben Spretz Gustavo Larsen Sandra Noriega Marianna Lucafò Eduardo Mansilla Chiara Garrovo Gustavo H. Marín Gabriele Baj Valter Gattei Gabriele Pozzato Luis Núñez Paolo Macor

Current B-cell disorder treatments take advantage of dose-intensive chemotherapy regimens and immunotherapy via use of monoclonal antibodies. Unfortunately, they may lead to insufficient tumor distribution of therapeutic agents, and often cause adverse effects on patients. In this contribution, we propose a novel therapeutic approach in which relatively high doses of Hydroxychloroquine and Chlo...

Journal: :Journal of the American Academy of Dermatology 2010
Charles Chiang Deborah Sah Bryan K Cho Blanca E Ochoa Vera H Price

BACKGROUND Lichen planopilaris (LPP) and its variant frontal fibrosing alopecia (FFA) are primary lymphocytic cicatricial alopecias for which there is no evidence-based therapy. OBJECTIVE We assessed the efficacy of hydroxychloroquine in active LPP and FFA using the LPP Activity Index (LPPAI), a numeric score that allows quantification of the symptoms and signs of the condition for statistica...

Journal: :Clinical and experimental rheumatology 1999
D J Hawley F Wolfe T Pincus

AIMS To describe the utilization of combination therapy in the treatment of rheumatoid arthritis (RA). METHODS Review of published articles and abstracts, and patient/physician questionnaire data. RESULTS Combination therapy was rarely used in the early 1980s and is now (1999) used for about 25% of RA patients in the US. Physician and patient surveys indicate that methotrexate plus hydroxyc...

Journal: :Antimicrobial agents and chemotherapy 2005
Jean-Marc Rolain Areen Boulos Marie-Noëlle Mallet Didier Raoult

Endocarditis is the major clinical manifestation of chronic Q fever. Although doxycycline along with hydroxychloroquine remains the mainstay of medical therapy for Q fever endocarditis, there are wide variations in the rapidity of the patient's decline of antibody levels during such therapy. We undertook a retrospective examination of whether there was any correlation between the ratio of serum...

2016
Tamarah D. de Jong Marjolein Blits Sander de Ridder Saskia Vosslamber Gertjan Wolbink Mike T. Nurmohamed Cornelis L. Verweij

BACKGROUND A peripheral blood interferon (IFN) signature (i.e., elevated type I interferon response gene [IRG] expression) has been described in a subset of patients with rheumatoid arthritis (RA). In the present study, we systematically assessed the association between this IRG expression and clinical parameters. METHODS Expression of 19 IRGs was determined in peripheral blood from 182 conse...

2017
Precil Diego Miranda de Menezes Neves Juliana Reis Machado Fabiano Bichuette Custódio Maria Luíza Gonçalves dos Reis Monteiro Shigueo Iwamoto Marlene Freire Marisa França Ferreira Marlene Antônia dos Reis

BACKGROUND Fabry Disease (FD) is a genetic disorder caused by alpha-galactosidase A deficiency. Certain drugs, such as hydroxychloroquine, can produce renal deposits that mimic morphological findings seen in FD, characterizing a type of drug-induced renal phospholipidosis. CASE PRESENTATION Case 1: A 28-year-old female patient with systemic lupus erythematosus who had been using hydroxychloro...

Journal: :Acta Dermato-Venereologica 1999

Journal: :British Journal of Ophthalmology 2008

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