BACKGROUND Non-alcoholic steatohepatitis (NASH) is a clinicopathological entity that is being recognized more frequently in recent years. This study aimed to evaluate the effects of Metformin, with and without a probiotic supplement on liver aminotransferases in patients with NASH. METHODS Sixty four patients 18-75 years with NASH confirmed by biopsy and histological assessment were enrolled ...

Objective(s):Lead (Pb) is a toxic metal inducing many destructive effects leading to a broad range of physiological, biochemical, and neurological dysfunctions in humans and laboratory animals. Materials and Methods: Here, we investigated the effect of chronic exposure to Pb (50 mg/l) on oxidative stress, hepatotoxicity, nephrotoxicity, and lipid profile of two different age groups of female r...

A stable activity which transfers the amino group from glutamate to prephenate was extracted from 4-day old etiolated shoots of sorghum. The activity was retained on DEAE cellulose and eluted as a single peak. Prephenate aminotransferase co-eluted with a very abundant alpha-ketoglutarate: aspartate aminotransferase, but heating at 70 degrees C resulted in loss of alpha-ketoglutarate: aspartate ...

Dexamethasone, insulin, and serum induce an additive increase in the activity of tyrosine aminotransferase (L-tyrosine : Z-oxoglutarate aminotransferase, EC 2.6.1.5) in hepatoma cells in tissue culture. By the criteria of immunotitration, heat stability, and electrophoresis on polyacrylamide gels, we have shown previously that all three effecters increase the cellular concentration of the same ...

an experiment was conducted to investigate the effects of using different levels of ginger rhizome powder (grp) and turmeric rhizome powder (trp) on production performance and some blood metabolites in laying hens. ninety 103-week old laying hens were divided into 5 treatments in a completely randomized design with 3 replicates and 6 birds in each cage. the birds were fed a corn-soybean meal ba...

background: this study aimed to assess several biochemical and oxidative stress parameters before and after radioiodine therapy in patients with well-differentiated thyroid cancer who consumed a low iodine diet and withdrawal of levothyroxine after total thyroidectomy. methods: we enrolled 40 candidates for radioiodine therapy. blood sampling was performed prior to as well as 72 h after consump...

The study aimed to examine the effect of extracted and standard ursolic acid in addition hyperinsulinemia compared vitamin B complex on liver kidney function alloxan-induced diabetic male rabbits. functions were determined analyzed by one–way a NOVA at variance software P-Value 0.05. result showed significant decrease aspartate aminotransferase (AST), alanine (ALT), alkaline phosphatase (ALP), ...

1,4-Butanediol is an industrial chemical used in the manufacture of other organic chemicals. It was nominated by the National Cancer Institute and selected for evaluation by the NTP because of high production volume, the potential for worker exposure, the lack of adequate toxicological characterization, and the lack of evaluation for carcinogenic potential. As documented in the scientific liter...