نتایج جستجو برای: hydrazides

تعداد نتایج: 849  

Journal: :Organic Letters 2021

Under superacidic conditions, aniline and indole derivatives are sulfonylated at low temperature with easy-to-access arenesulfonic acids or arenesulfonyl hydrazides. By modification of the functional-group directing effect through protonation, this method allows nonclassical site functionalization by overcoming innate regioselectivity electrophilic aromatic substitution. This superacid-mediated...

2008
Muhammad Zia-ur-Rehman Mark R. J. Elsegood Shahid Mahmud Hamid Latif Siddiqui

In the title compound, C(8)H(8)N(4)O(5), the nitro groups ortho and para to the hydrazone group are twisted by 10.0 (2) and 3.6 (2)°, respectively, relative to the aromatic ring. The structure exhibits an intra-molecular N-H⋯O hydrogen bond between the hydrazide and ortho-nitro groups. There is a strong inter-molecular C=O⋯H-N hydrogen bond, giving rise to chains, and weaker ONO⋯NO(2) [2.944 (2...

Journal: :Acta pharmaceutica 2004
Monika Wujec Monika Pitucha Maria Dobosz Urszula Kosikowska Anna Malm

In the reaction of hydrazide of thiophene-2-acetic acid (1) with isothiocyanates, the respective thiosemicarbazides 2a-g were obtained. Further cyclization with 2% NaOH led to formation of 4-substituted-3-(thiophene- 2-yl-methyl)-Delta2-1,2,4-triazoline-5-thiones (3a-g). These compounds showed promising antimycotic activity.

2007
Hoong-Kun Fun Suchada Chantrapromma Subrata Jana Anita Hazra Shyamaprosad Goswami

In the mol-ecular structure of the title hydrazide derivative, C(18)H(26)N(4)O(4), the conformations of the two units of 2-(2,2-dimethyl-1-oxoprop-yl)hydrazide substituents are not planar; these two units are attached axially to the benzene ring with C(ortho)-C-C(=O)-N torsion angles of 28.1 (2) and 31.0 (2)° [where C(ortho) is the C atom at position 4 of the benzene ring relative to the substi...

2013
Sergiy I. Kovalenko Lyudmyla M. Antypenko Andriy K. Bilyi Sergiy V. Kholodnyak Olexandr V. Karpenko Olexii M. Antypenko Natalya S. Mykhaylova Tetyana I. Los Olexandra S. Kolomoets

The combinatorial library of novel potential anticancer agents, namely, 2-(alkyl-, alkaryl-, aryl-, hetaryl-)[1,2,4]triazolo[1,5-c]quinazolines, was synthesized by the heterocyclization of the alkyl-, alkaryl-, aryl-, hetarylcarboxylic acid (3H-quinazoline-4-ylidene)hydrazides by oxidative heterocyclization of the 4-(arylidenehydrazino)quinazolines using bromine, and by the heterocyclization of...

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