نتایج جستجو برای: human testicular stem cells

تعداد نتایج: 2741032  

Fatemeh Naseri Malihe Akbarzadeh Niaki, Maryam Moghaddam Matin Masoud Fereidoni Nasser Mahdavi Shahri, Somayeh Naderi

The aim of this study was to investigate the interactions between rat intestine decellularized scaffold and human adipose derived mesenchymal stem cells. Rat large intestine was dissected in fragments and decellularized by physicochemical methods. The scaffolds were loaded by human adipose derived mesenchymal stem cells expressing green fluorescent protein. Microscopic sections were prepared fr...

حسینی پناه, سیدمحمد, زمانی, علیرضا, طالب زاده, فهمیه, فضلی, حسین, پورجعفری, حمید, پورجعفری, بهاره,

Introduction & Objective: Stem cells are determined by their unique features. One of them is high proliferation ability and the other is potency of differentiation to various tissues. The results of new works in various countries around the world including Iran show the growing momentum of works on stem cell therapy. Working with stem cells from different origins including the cells originate...

Journal: :Human reproduction 2010
S C Mizrak J V Chikhovskaya H Sadri-Ardekani S van Daalen C M Korver S E Hovingh H L Roepers-Gajadien A Raya K Fluiter Th M de Reijke J J M C H de la Rosette A C Knegt J C Belmonte F van der Veen D G de Rooij S Repping A M M van Pelt

BACKGROUND Given the significant drawbacks of using human embryonic stem (hES) cells for regenerative medicine, the search for alternative sources of multipotent cells is ongoing. Studies in mice have shown that multipotent ES-like cells can be derived from neonatal and adult testis. Here we report the derivation of ES-like cells from adult human testis. METHODS Testis material was donated fo...

Journal: :Journal of the National Cancer Institute. Monographs 2005
Kyle E Orwig Stefan Schlatt

The existence of spermatogonial stem cells in the testis offers clinically relevant options for preservation and restoration of male fertility. New approaches based on male germ cell transplantation and testicular tissue grafting can be applied to generate a limited number of sperm cells and could therefore be considered important new avenues for restoration of fertility in oncological patients...

2018
Maxime Vermeulen Federico Del Vento Francesca de Michele Jonathan Poels Christine Wyns

Cryopreservation of immature testicular tissue before chemo/radiotherapy is the only option to preserve fertility of cancer-affected prepubertal boys. To avoid reintroduction of malignant cells, development of a transplantable scaffold by decellularization of pig immature testicular tissue (ITT) able to support decontaminated testicular cells could be an option for fertility restoration in thes...

Journal: :cell journal 0

objective: the neural crest is a transient structure of early vertebrate embryos that generates neural crest cells (nccs). these cells can migrate throughout the body and produce a diverse array of mature tissue types. due to the ethical and technical problems surrounding the isolation of these early human embryo cells, researchers have focused on in vitro studies to produce nccs and increase t...

Journal: :modares journal of medical sciences: pathobiology 2014
mahnaz haddadi zohreh mazaheri saeid amanpour samad muhammadnejad ahad muhammadnejad

objective: it is hypothesized that stem cells have the capability to form tumors after transplantation. spermatogonial stem cells have proliferation potency and colonization ability related to express pluripotency genes such as c-myc. the primary aim of this study is to investigate tumorigenicity ability of these cells after in vitro cultivation and inoculation in athymic animals. methods: sper...

Fakher Rahim Gholamreza Khamisipour Masoud Soleimani Najmaldin Saki Seyed Hadi Mousavi

Human mesenchymal stem cells (hMSCs), which also called mesenchymal stromal cells, are multipotent stem cell. Human MSCs typically are positive for the surface markers CD44, CD73, CD90, CD105, CD106, and also negative for hematopoietic markers CD34 and CD45.These cells can be isolated from postnatal bone marrow, adipose tissue, placenta, and scalp tissue, as well as from various fetal tissues. ...

Journal: :journal of cell and molecular research 0

stem cells are the cells having some distinguishing characteristics like longevity, high capacity of self-renewal and differentiation, quiescence and highly error-free proliferation. almost all stem cells have the potential of lineage reprogramming, i.e. inter-conversion of cell lineages. they also have the potential to differentiate into almost all kinds of cells. these cells have been found i...

Hair loss is a common hair disorder in human population. It affects quality of life and there are ongoing attempts to find permanent treatment for this condition. But, today there is no completely safe and protective treatment for all. Hair follicle stem cells are alive, but quiescence in androgenetic alopecia and are potentially active and can proliferate and differentiate, then regenerate hai...

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