In most mammalian species aromatase is encoded by a single gene (Cyp19), which contains 18 exons, nine of them being translated. In man, the presence of a biologically active aromatase and oestrogen receptors (ERalpha and ERbeta) has been reported in Leydig cells, and also in immature germ cells and ejaculated spermatozoa. Concerning aromatase, the amount of transcript and enzymatic activity ar...

in recent years, preservation of fertility in women has been of great importance, especially in patients exposed to deleterious conditions on fertility. thus, cryopre-servation of human gametes, embryos and ovarian tissue has become an essential part of assisted reproduction. this approach limits the number of embryos transferred, while supernumerary oocytes and/ or embryos can be used in subse...

toxoplasma gondii is an apicomplexan parasite that infects human and almost all warm-blooded animals. the life cycle of the parasite includes an asexual reproduction in intermediate hosts (mammals and birds) and a sexual reproduction in definitive hosts (felidae). cats are both the intermediate and the definitive host for t. gondii. the aim of this study was to investigate anti-t. gondii antibo...

regarding extensive domain of islamic teachings including all aspects of human life following as individual, social, spiritual, physical and material issues and noting close relations of the humanities with this dimensions, a deep bond between islam and the humanities including management and education is revealed. to attain an islamic understanding of relationship between the dimensions of the...

BACKGROUND There is a growing body of epidemiologic literature reporting associations between atmospheric pollutants and reproductive outcomes, particularly birth weight and gestational duration. OBJECTIVES The objectives of our international workshop were to discuss the current evidence, to identify the strengths and weaknesses of published epidemiologic studies, and to suggest future direct...

Chlamydia trachomatis infections are the most prevalent bacterial sexually transmitted infections (STI) recognized throughout the world. Worldwide, the magnitude of morbidity associated with sexually transmitted chlamydial infections is enormous. C.trachomatis is a common cause of urethritis and cervicitis, and sequelae include pelvic inflammatory disease (PID), ectopic pregnancy, tubal factor ...

J Obstet Gynaecol Can 2012;34(6):511–513 I is customary in obituaries to eulogize the deceased— to fondly remember their accomplishments, even if these were few and fleeting. Were I to write an obituary for Assisted Human Reproduction Canada (AHRC)1— the federal agency established “to protect and promote the health and safety, and the human dignity and human rights, of Canadians and to foster t...

p63 is a transcriptional factor implicated in cancer and development. The presence in TP63 gene of alternative promoters allows expression of one isoform containing the N-terminal transactivation domain (TA isoform) and one N-terminal truncated isoform (ΔN isoform). Complete ablation of all p63 isoforms produced mice with fatal developmental abnormalities, including lack of epidermal barrier, l...

Obesity influences human reproduction in several ways. Obesity is associated with sub-fertility and this effect is noticeable already at BMI 25 kg/m. As many as 6 9% of the female population of child-bearing age suffer from polycystic ovary syndrome, i.e. anovulatory infertility, among whom more than half are obese. Bariatric surgery has become increasingly common in women of childbearing ages,...